1994
DOI: 10.1016/0954-6111(94)90063-9
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Lobar atelectasis in cystic fibrosis and treatment with recombinant human DNase I

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Cited by 26 publications
(11 citation statements)
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“…MR can detect atelectasis as on CT. This is a highly relevant observation, seeing that atelectasis is associated with poor outcome and requires aggressive medical treatment (53–55). MRI was used to evaluate treatment effectiveness in one patient and showed complete resolution of the atelectasis (Fig.…”
Section: Discussionmentioning
confidence: 99%
“…MR can detect atelectasis as on CT. This is a highly relevant observation, seeing that atelectasis is associated with poor outcome and requires aggressive medical treatment (53–55). MRI was used to evaluate treatment effectiveness in one patient and showed complete resolution of the atelectasis (Fig.…”
Section: Discussionmentioning
confidence: 99%
“…(3) increased cough; (4) fever (38°C); (5) increased wheezing; (6) decreased exercise tolerance, malaise, fatigue, or lethargy; (7) FEVX or FVC decreased 10% from a previously recorded value; (8) radiographic changes indicative of a new pulmonary process; or (9) changes in chest sounds. A non-PDE (NPDE) was noted when a patient had fewer than four of the above abnormalities.…”
Section: Methodsmentioning
confidence: 99%
“…Surfactant administration was reported to improve ventilation by re-aeration of atelectatic regions and help wean children from mechanical ventilation [161]. Similarly, bronchoscopically administered recombinant human DNase has been used in cystic fibrosis patients [162], non-cystic fibrosis patients [163], and premature neonates [164], with variable success.…”
Section: Atelectasis Treatmentmentioning
confidence: 99%