“…Lead can cause neurological, gastrointestinal and bone changes resulting from depletion of calcium (Chang et al, 2013;Sabbar et al, 2012;Nascimento et al, 2010;Pereira and Rodrigues, 2013). Since copper can cause liver abnormalities, skin lesions and bleeding (Kumar et al, 2011;Kyzas et al, 2013), zinc may induce anemia, reduce immune frame, cardiovascular disorders (hypertension and arrhythmias), gastrointestinal disorders (ulcer) and skin lesions (Bennett et al, 1997;Agourakis et al, 2006).…”