Liver Morphology of Potential Live Donors of Segments of Liver

Iljinsky, I. M.; Kurenkova, Lubov G.; Schkalova, L.; Минина, М. Г.; Ammosov, A. A.; Moysyuk, Ya. G.; Цирульникова, О. М.; Gautier, Sophie

doi:10.1097/00007890-201007272-01532

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“…Available publications on the subject are ambiguous, and they do not contain all of the data on morphologic criteria, which suggest the need for further research in this area. [1][2][3] The histology study is the preferred method for assessing the suitability of a donor liver. To verify the morphologic condition of the liver, a liver biopsy is performed in patients who are potential deceased or living donors.…”

Section: Introductionmentioning

confidence: 99%

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Shaimardanova

Fedotovskikh²,

Савчук³

et al. 2015

Exp Clin Transplant

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Objectives: The pathologic evaluation of the liver is one of the most important issues in liver transplants. We evaluated the histopathological condition of livers in potential donors. Materials and Methods: After liver biopsy, 37 potential donor livers were histologically studied. Liver tissue was stained by hematoxylin and eosin as well as Masson Trichrome. Results: The results of the study showed the morphologic criteria used to estimate the state of the liver in potential donors is not only steatosis and fibrosis, but other important histologic criteria, such as proteinosis, necrosis of hepatocytes, endotheliitis of central veins, inflammatory infiltration, endarteritis in portal tracts and phlebitis in portal tracts, proliferation of the bile ducts, and cholestasis. Conclusions: Results of the study showed that the morphologic criteria to estimate the state of the liver in potential donors includes not only steatosis and fibrosis, but other important histologic criteria as well.

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Section: Introductionmentioning

confidence: 99%