Liver Enzyme Levels in Arthritis Patients Treated with Long‐Term Bolus Methotrexate

Aponte, Julio; Petrelli, Mary; Dawson, Neal V.

doi:10.1002/art.1780350123

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…In the last few years, the efforts of clinical investigators have mainly been directed towards two drugs, methotrexate [10][11][12][13] and sulphasalazine [14][15][16][17], which have a favour able effect on the cutaneous and the articular manifestations of PsA. More recently, other compounds (colchicine [18], cyclosporine A [18][19][20], bromocriptine [21], 1,25-dihy droxy vitamin D, [22] and etretinate [23]) have been tested, but their efficacy needs to be confirmed in larger double blind trials.…”

Section: Treatmentmentioning

confidence: 99%

Current Concepts in Psoriatic Arthritis

Veys

Mielants²

1994

Dermatology

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Psoriatic arthritis is an inflammatory arthropathy associated with psoriasis and characterized by absence of rheumatoid factor. Any form of psoriasis can be complicated by joint inflammation. Four groups have been identified: pauciarticular psoriatic arthritis, psoriatic spondylitis, symmetrical polyarticular psoriatic arthritis and arthritis mutilans. The etiology of psoriatic arthritis remains unclear. Genetic, immunologic and environmental factors are thought to be important in the development of the disease. The role of cytokines and adhesion molecules in the mechanism of joint destruction is highlighted, and recent therapeutic strategies are discussed.

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