“…In the last few years, the efforts of clinical investigators have mainly been directed towards two drugs, methotrexate [10][11][12][13] and sulphasalazine [14][15][16][17], which have a favour able effect on the cutaneous and the articular manifestations of PsA. More recently, other compounds (colchicine [18], cyclosporine A [18][19][20], bromocriptine [21], 1,25-dihy droxy vitamin D, [22] and etretinate [23]) have been tested, but their efficacy needs to be confirmed in larger double blind trials.…”