Liver and Gastrointestinal Manifestations of Dengue Hemorrhagic Fever. An Analysis from a Cohort of 263 Hospitalized Patients

Medina, Antonio Ramos‐De la; Cerón, Tadeo; Díaz-Vega, Aurora; Hernandez, Angelica; Remes-Troche, José María

doi:10.14309/00000434-200709002-00257

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“…These findings are also observed in previously conducted multiple studies. [13][14][15] But, the prevalence of GI manifestations has varying prevalence in different studies such as study conducted by La Medina 16 has observed 50% prevalence in Mexico and authors from Spain has observed 100% prevalence of gastrointestinal symptoms in patients with dengue. 17 In our study the most common GI manifestations was presence of nausea/vomiting in 70.64% of the patients.…”

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confidence: 99%

Frequency of Gastrointestinal Signs and Symptoms in Patients with Dengue Fever in Tertiary Care Hospital

Abrar¹,

Selamat²,

Abbasi³

et al. 2023

PJMHS

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Objective: The objective behind this study was to determine the frequency of gastrointestinal signs and symptoms in patients with dengue fever in tertiary care hospital Methods: A cross sectional observational study was conducted on all adult patients diagnosed with dengue disease after taken informed consent from the patients and approval from the ethical committee of the hospital. All these patients were evaluated for the presence or absence of gastrointestinal (GI) manifestations. Those who had GI symptoms were further evaluated for the frequency of different types of GI symptoms. All baseline and clinical data were taken using a structured questionnaire and then entered & analysed using SPSS v. 26. Results: A total of 174 patients who were dengue virus positive were included for final analysis. Overall mean age and SD was 29.22±8.14 years and majority belongs to young age group, ≥16 – 40 years (60.11%, n = 104). Most of our study participants were males (75.86%, n = 132). Hypertension was the most common comorbid condition observed in our study participants (12.06%, n = 21). The overall prevalence of GI manifestations in our study who were dengue positive was 62.64% (n = 109). The most common GI symptom was presence of nausea/vomiting (70.64%, n = 77). Conclusion: The prevalence of GI manifestations in patients with dengue is quite high. Nausea/vomiting was the most common GI manifestation while patients with hepatomegaly and GI bleeding were also prevalent. Keywords: Dengue fever, gastrointestinal symptoms, clinical manifestation, Pakistan

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