Frequency of Gastrointestinal Signs and Symptoms in Patients with Dengue Fever in Tertiary Care Hospital

Abstract

Objective: The objective behind this study was to determine the frequency of gastrointestinal signs and symptoms in patients with dengue fever in tertiary care hospital Methods: A cross sectional observational study was conducted on all adult patients diagnosed with dengue disease after taken informed consent from the patients and approval from the ethical committee of the hospital. All these patients were evaluated for the presence or absence of gastrointestinal (GI) manifestations. Those who had GI symptoms were further evaluated for the frequency of different types of GI symptoms. All baseline and clinical data were taken using a structured questionnaire and then entered & analysed using SPSS v. 26. Results: A total of 174 patients who were dengue virus positive were included for final analysis. Overall mean age and SD was 29.22±8.14 years and majority belongs to young age group, ≥16 – 40 years (60.11%, n = 104). Most of our study participants were males (75.86%, n = 132). Hypertension was the most common comorbid condition observed in our study participants (12.06%, n = 21). The overall prevalence of GI manifestations in our study who were dengue positive was 62.64% (n = 109). The most common GI symptom was presence of nausea/vomiting (70.64%, n = 77). Conclusion: The prevalence of GI manifestations in patients with dengue is quite high. Nausea/vomiting was the most common GI manifestation while patients with hepatomegaly and GI bleeding were also prevalent. Keywords: Dengue fever, gastrointestinal symptoms, clinical manifestation, Pakistan

Resurgence of Dengue Virus Serotype 4 in Malaysia: A Comprehensive Clinicodemographic and Genomic Analysis

“…According to one study [ 33 ], gastrointestinal bleeding complicated 4.4% of dengue infections, and according to another [ 34 ], a vast majority of patients experiencing gastrointestinal symptoms required hospitalisation. Therefore, it is critical to recognise the significance of gastrointestinal symptoms in dengue patients as soon as possible for a number of reasons, including the potential financial impact on patients and their families and the possibility that early diagnosis could prevent these patients from being admitted to the intensive care unit [ 35 ].…”