Livedo Reticularis with Summer Ulcerations

Feldaker, Mauri

doi:10.1001/archderm.1955.03730310033007

Cited by 92 publications

(43 citation statements)

References 11 publications

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“…Several patients with winter ulcerations had acrocyanosis in addition to the livedo reticularis, and digital arterial occlusion with associated ulcerations of the toes was noted in seven patients, of whom three had Raynaud's phenomena. Hypertension was noted in several patients with winter ulcerations, as recorded in table 1 confluent eruption develope(l, which was confined to the lower extremities from knees to ankles followed l)y residual brownish hyperpigmentation. Two weeks afterward, there dlevelope(l a buirning sensation of the ankles, swelling of both feet and small red spots over the lateral malleoli of the ankles which subsequently became 'b}listers" anld ulcers with (Irainage of serosanguineous fluid, crusting and finally healing.…”

Section: Clinical Types Of Livedo Livedo Reticularis Is Best Classifimentioning

confidence: 90%

“…' The first part of this report will briefly summarize some of the medical literature concerning livedo reticularis, and the second part will contain the data on winter and summer ulcerations in livedo reticularis. 1 * Unless otherwise designated, the term "livedo reticularis," when mentioned in this report, applies to idiopathic livedo reticularis, not to symptomatic livedo reticularis as a result of such diseases as periarteritis nodosa or which has been described with tuberculosis or syphilis.…”

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confidence: 97%

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Livedo Reticularis with Ulcerations

Feldaker¹,

Hines²,

Kierland³

1956

Circulation

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Idiopathic livedo reticularis may be associated with ulcerations of the lower extremities beginning primarily during the warmer or summer months, as well as the more usual occurrence of winter ulcerations. Summer ulceration apparently is a new and rare entity which has many clinical and histopathologic features similar to winter ulcerations. Hypertension, Raynaud's phenomena, acrocyanosis and thrombosis of digital arteries were noted only in patients with winter ulcerations, while edema of the legs and feet was a more prominent feature in patients with summer ulcerations. Medical treatment, including rest in bed, elastic supportive bandages and a trial of hexamethonium (bistrium bromide) injections, seemed to be the treatment of choice. Lumbar sympathectomy did not seem to be of great permanent value.

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Section: Clinical Types Of Livedo Livedo Reticularis Is Best Classifimentioning

confidence: 90%

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confidence: 97%

Livedo Reticularis with Ulcerations

Feldaker¹,

Hines²,

Kierland³

1956

Circulation

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“…They described thickening and hyalinization usually in the walls of dermal arterioles and sometimes dilatation of the lumen or proliferation of the endothelial cells with occlusion or thrombosis. Ff.ldaker et al [9] have described similar changes in the large vessels of the deep dermis and subcutis as well. The minimal inflammatory reaction and the prolifera tion of new capillaries with considerable endothelial prominence have also been described by these authors but have been considered unimportant.…”

Section: Commentmentioning

confidence: 77%

A Peripheral Vascular Syndrome Overlapping with Systemic Lupus Erythematosus

Johansson¹,

Niemi²,

Mustakallio³

1977

Dermatology

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Three women and five men with chronic biological false-positive seroreactions for syphilis and circulating anticoagulants exhibited a vascular syndrome consisting of recurrent deep venous thrombosis of the extremities and necrotizing purpura with painful superficial starlike ulcers around the ankles. The skin biopsies revealed a unique picture of massive proliferation of hemorrhagic dermal capillaries without a significant inflammatory reaction. Some virus infection may function as a trigger of this peripheral vascular syndrome, because 6 of the 8 patients had a preceding pneumonia with pleural effusion. Considering that the three women had clinical and laboratory evidence of systemic lupus erythematosus (SLE) this syndrome may be related to SLE.

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“…Hautklinik des Universitätsklinikum Münster University Hospital of Dermatology, Münster, Germany Einleitung Die Livedovaskulopathie wurde erstmalig in den 50er Jahren von Feldaker als Gerinnungsleiden beschrieben und als Livedo reticularis mit Sommer-Ulzerationen bezeichnet [1]. Der später verwendete Begriff der segmentalen hyalinisierenden Vaskulitis impliziert histologische Erscheinungen der Erkrankung, betont jedoch irreführend den entzündlichen Aspekt [2].…”

Section: Nina Kerk Tobias Goergeunclassified

Livedovaskulopathie – Aktuelles zur Diagnostik und Therapie des Hautinfarkts

Kerk

Goerge

2013

J Deutsche Derma Gesell

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Die Livedovaskulopathie ist eine seltene, chronisch rezidivierende Erkrankung der kutanen Mikrozirkulation. Klinisch manifestiert sie sich typischerweise als Trias aus Livedo racemosa der Haut, episodischem Auftreten von schmerzhaften Ulzerationen an der unteren Extremität und Abheilung dieser Ulzerationen unter Ausbildung von kleinen porzellanartigen Narben, der sogenannten Atrophie blanche. Forschungsbemühungen der letzten Jahre haben gezeigt, dass die Livedovaskulopathie als Gerinnungsleiden von den primär entzündlichen Vaskulitiden abzugrenzen ist. Diese Differenzierung trägt zum besseren pathophysiologischen Verständnis bei und stützt zudem die therapeutischen Überlegungen im Hinblick auf den Einsatz neuer systemischer Antikoagulanzien. Die Verhinderung irreversibler Narbenbildung und die Verbesserung der Lebensqualität der betroffenen Patienten sind Hauptziele der Therapie des Hautinfarktes und erfordern frühzeitiges konsequentes Vorgehen. Der vorliegende Artikel stellt das aktuelle Wissen zur Diagnosefindung dieser seltenen Erkrankung dar und bietet eine praktische Anleitung zur Therapie der Livedovaskulopathie. SummaryLivedoid vasculopathy is a rare, chronic, recurrent disease of the cutaneous microcirculation. Its typical clinical manifestation is a triad which consists of livedo racemosa of the skin, episodic painful ulcerations of the distal aspects of the legs and a healing process leaving small porcelain-white scars called atrophie blanche. As an important result of recent research, livedoid vasculopathy has been defined as a coagulation disorder classified as a vasculopathy different from inflammatory vasculitis. This differentiation adds to the current pathophysiologic understanding and supports the therapeutic rationale with respect to the use of new systemic anticoagulants. The prevention of irreversible residual scarring and the improvement of patients' quality of life are the main goals in treating cutaneous infarction and require early and consequent treatment. This article presents current knowledge on diagnosing this rare disease and offers practical guidance on its therapy.

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Livedo Reticularis with Summer Ulcerations

Cited by 92 publications

References 11 publications

Livedo Reticularis with Ulcerations

Livedo Reticularis with Ulcerations

A Peripheral Vascular Syndrome Overlapping with Systemic Lupus Erythematosus

Livedovaskulopathie – Aktuelles zur Diagnostik und Therapie des Hautinfarkts

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