Literature Review: Potential Pharmacological Activity of Luffa cutangula L. Roxb

Abstract

Indonesia is a fertile country with various kinds of herbal plants that can grow in it. This situation has led to the widespread use of herbs in society and has even become part of Indonesian culture. There are various empirical results from the use of herbal plants in Indonesia. Luffa acutangula (gambas) is one of the many plants found in Indonesia. This plant has been widely used in helping to treat various diseases. A journal search was conducted on the pharmacological activity of Luffa acutangula in the early stages of pre-clinical trials (in vitro and in vivo) and then presented in a literature review to prove the empirical benefits of this herb. The results of potential pharmacological activities of Luffa acutangula include antimicrobial, antiparasitic, anticancer, antioxidant, antiinflammatory, antithyroid, hypoglycemic treatment, analgesic, immunomodulatory, hepatoprotective, and gastroprotective. The results of a literature review study on the pharmacological activity of Luffa acutangula show evidence of pre-clinical empirical benefits. It is hoped that by obtaining more comprehensive data like this literature study, it is hoped that it will serve to collect information on the use of Luffa acutangula as a medicinal preparation.

Characterization of Sesuvium sesuvioides Using High-Performance Liquid Chromatography and Validation of Its In Vivo Anti-hyperthyroidism Effect via Suppressing Oxidative Stress and Inflammatory Markers

“…The use of natural products or medicinal plant materials to treat thyroid problems has yet to be investigated. It has been observed that many plants that exhibit tyrosine in their constituents are considered responsible for the production of thyroid hormones [triiodothyronine (T 3 ) and vera, 9 Hippophae rhamnoides, 10 Luffa acutangula, 11 and Abutilon indicum 12 were previously reported. Similarly, several herbaceous plants from the Cholistan Desert (Pakistan) are used to treat different illnesses.…”

“…It has been observed that many plants that exhibit tyrosine in their constituents are considered responsible for the production of thyroid hormones [triiodothyronine (T 3 ) and T 4 ]. Plants with antihyperthyroidism potential, such as Ficus racemosa, Aloe vera, Hippophae rhamnoides, Luffa acutangula, and Abutilon indicum were previously reported.…”

Morphological Characteristics and Growth Behavior of Ridge Gourd [Luffa acutangula (L.) Roxb.] in Tropical Urban Ecosystem

“…Harfiani et al [11] stated that the leaf of ridge gourd contained many beneficial phytochemicals for human health, including alkaloids, glycosides, saponins, carbohydrates, amino acids, lipids, steroids, terpenoids, and triterpenoids. Therefore, ridge gourd provides additional benefits in its edible young leaves besides the fruits.…”