Listeriosis during pregnancy

Abstract

Pregnancy-associated listeriosis should be considered as a cause of fever during pregnancy and appropriate treatment should be initiated preemptively. Prevention remains the best way to control listeriosis and should be reinforced among patients, health care professionals, and regulatory agencies.

Prevalence, Pathogenicity, Virulence, Antibiotic Resistance, and Phylogenetic Analysis of Biofilm-Producing Listeria monocytogenes Isolated from Different Ecological Niches in Egypt: Food, Humans, Animals, and Environment

“…PCR screening of four key internalins encoded by inlA, inlB, inlC, and inlJ indicated the presence of all four genes in 12 isolates, including the isolates from veterinary and clinical samples, while it was absent in two of the isolates (1/3 from each of the broilers and layers). The frequency of the individual internalin genes inlA, inlB, inlC, and inlJ were 74.1% (20), 81.5% (22), 70.4% (19), and 66.7% (18), respectively. Notably, the isolates (4) from cow, she-camel, and buffalo milk, and the two isolates that caused septicemia, were positive for the presence of all 11 genes examined.…”

“…Although the genus Listeria includes many species, due to the pathogenicity of L. monocytogenes in human hosts and its ability to flourish in hostile environments, earlier research implicating genome sequencing were to a great extent concentrated on L. monocytogenes [7][8][9][10][11]. L. monocytogenes is implicated with human listeriosis and in the present decennium, numerous serious outbreaks of foodborne listeriosis have been recorded in different countries and continents [11][12][13][14][15][16], causing serious manifestations in the form of septicemia and meningitis, principally in the immunocompromised and old populaces in addition to pregnant women, who may bring forth stillborn babies or seriously contaminated infants [4,9,[17][18][19][20][21][22][23][24][25][26].…”

The epidemiology of listeriosis in pregnant women and children in New Zealand from 1997 to 2016: an observational study

“…Listeriosis most commonly presents in the third trimester of pregnancy (from 28 weeks) and is rarely fatal in the mother, particularly in the absence of coexisting medical conditions [11,12]. Later infection, particularly that within the third trimester, is typically associated with more favourable foetal outcomes than earlier infection [13]. If transmission to the foetus does occur, infection can lead to miscarriage, preterm delivery or stillbirth.…”

Listerioza – rzadka choroba o poważnym rokowaniu

“…Listerioza u kobiet ciężarnych występuje 18-krotnie częściej niż w pozostałej części populacji. Zakażenie może być przyczyną poronienia, obumarcia płodu, porodu przedwczesnego, sepsy, zapalenia płuc, niewydolności oddechowej lub zapalenia opon mózgowo-rdzeniowych u noworodków [3,9]. Do zainfekowania L. monocytogenes noworodka może dochodzić przez łożysko, poprzez aspirację zakażonego płynu owodniowego lub z powodu zakażenia wstępującego z pochwy (zakażenia prenatalne) oraz w trakcie porodu podczas przechodzenia noworodka przez kanał rodny, gdy pochwa jest skolonizowana przez pałeczki L. monocytogenes (zakażenia perinatalne) [1,3,4,5].…”

“…Częstość występowania listeriozy w okresie noworodkowym szacowana jest na 8,6/100 000 żywych urodzeń. Choroba ta zazwyczaj cechuje się ostrym przebiegiem oraz wysokim odsetkiem przypadków śmiertelnych (20-60%) [5,9]. Zakażenie może przebiegać jako postać wczesna (early-onset infection) -do 5. doby życia (d.ż.)…”