Listeria monocytogenes infection in patients with cancer

Rivero, Gustavo; Torres, Harrys A.; Rolston, Kenneth V. I.; Kontoyiannis, Dimitrios P.

doi:10.1016/s0732-8893(03)00116-0

Cited by 60 publications

(29 citation statements)

References 29 publications

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“…ABPC is the most frequently used antibiotic for the treatment of human listeriosis [14]. In our study, all of the isolates were susceptible, and the MIC 50 and MIC 90 values were 0.5 g/ml ( Table 2), indicating that the MICs of isolates for ABPC were very low.…”

mentioning

confidence: 57%

Antimicrobial Susceptibilities of Listeria monocytogenes Isolated in Japan

Okada¹,

Okutani²,

Suzuki³

et al. 2011

The Journal of Veterinary Medical Science

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ABSTRACT. The antimicrobial susceptibility of 201 Listeria monocytogenes isolates from foods, environments, animals and human patients in Japan was determined. All isolates were susceptible to ampicillin, the first choice of drug for listeriosis treatment, chloramphenicol, dihydrostreptomycin, erythromycin, enrofloxacin, gentamicin, kanamycin, lincomycin, nosiheptide, salinomycin, vancomycin, and virginiamycin. A human strain was resistant to oxytetracycline. The Minimum Inhibitory Concentration (MIC) for 50% of the strains and the MIC for 90% of the strains were comparable in all the isolates. This is the first investigation to compare antibiotic resistances between isolates from foods and isolates from human patients in Japan. The result showed that most of the isolates were susceptible to antibiotics used in this study.

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mentioning

confidence: 57%

Antimicrobial Susceptibilities of Listeria monocytogenes Isolated in Japan

Okada¹,

Okutani²,

Suzuki³

et al. 2011

The Journal of Veterinary Medical Science

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“…Other populations at risk include adults with underlying disease such as cancer, HIV infection, chronic hepatic disorders, and diabetes [83]. Individuals at particular risk include those with abnormalities in T-cell-mediated immunity, such as patients with solid organ or bone marrow transplants who are receiving adrenal corticosteroids [80].…”

Section: Enteric Infectionsmentioning

confidence: 99%

Important emerging bacterial zoonotic infections affecting the immunocompromised

2005

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-The immunocompromised are at particular risk for infection with zoonotic diseases. Persons can be temporarily immunocompromised due to pregnancy or developmental stage (i.e. infants); longer-term or permanent states of immunosuppression can occur as a result of immunosuppressive treatment following cancer or organ transplant, or from infectious diseases, such as AIDS. The focus of this review article is on emerging bacterial zoonotic diseases that are of particular concern among the immunocompromised. Factors that affect disease emergence can include factors such as human demographics and behavior; technology and industry; economic development and land use; international travel and commerce; microbial adaptation and change; and breakdown of public health measures. The immunocompromised need to take precautions when engaging in seemingly normal activities such as food preparation; caring for companion animals; and recreational or occupational activities. The immunocompromised are not only more susceptible to infection, but often suffer more serious sequelae as a result of infection. This review article provides an overview of the major foodborne, respiratory, and vector-borne bacterial pathogens that affect the immunocompromised. The major categories of immunodeficiency are described. In addition, measures that can be taken to prevent infection, including the role of health education, are discussed.

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“…9 Ri ve ro et al re por ted the largest gro up consisting of 11 pa ti ents with L. mo nocy to ge nes in fec ti on af ter BMT. 10 The most com mon and sha red fin dings in the se ca se re ports we re chronic GVHD and cor ti cos te ro id use which we re compa rab le to our ca se but the se re por ted ca ses sur vi ved af ter the an ti bi ot he rapy unlike our ca se. This is the first ca se of me nin gi tis re por ted due to L. mo nocy to ge nes af ter al lo ge ne ic BMT in our co untry.…”

Section: Discussionmentioning

confidence: 60%

isteria Monocytogenes Meningitis After Allogeneic Bone Marrow Transplantation in a Patient with Myelodysplastic Syndrome-Refractory Anemia with Excess Blasts: Case Report

Alkan¹,

Timurağaoğlu²,

Saba³

et al. 2010

Turkiye Klinikleri J Med Sci

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isteria monocytogenes is a gram positive aerobic bacterium invading macrophages and epithelium and it enters the body via gut following ingestion of contaminated foods. Besides the virulence of the bacteria, cellular immunity is also important for defense against this microorganism. It usually causes a mild gastroenteritis but rarely meningitis in healthy people.1 Life threatening bacteriemia and meningitis caused by L. monocytogenes are generally seen in newborns, geriatric population and immunosuppressive patients including organ recipients. 2,3 We presented a patient with meningitis due to L. monocytogenes after allogeneic BMT, a rarely reported case in the literature. A AB BS S T TR RA AC CT T Viral, fungal and bacterial infections are commonly seen in patients early after the allogeneic bone marrow transplantation (BMT), because of neutropenia in the early period, later they occur due to cell mediated immune deficiency and at the late post transplant period due to immunoglobulin deficiency. Listeria monocytogenes is a gram positive bacterium that invades and proliferates in macrophages and epithelium. Because it is an intracellular bacterium, besides its virulence, host immune system is also important for defence mechanism against bacterium. Life threatening bacteriemia and meningitis caused by L. monocytogenes are generally seen in newborns, elderly and immunosuppressive patients including organ recipients. Herein we reported a patient who had allogeneic BMT due to myelodysplastic syndrome-refractory anemia with excess blasts (MDS-RAEB), presented with L. monocytogenes meningitis six months after allogeneic transplantation.K Ke ey y W Wo or rd ds s: : Bone marrow transplantation; immunosuppression; meningitis, listeria Ö ÖZ ZE ET T Allogeneik kök hücre nakli sonrası akut dönemde nötropeni, daha sonra hücresel immun yetmezlik ve son dönemde de hipogamaglobulinemi nedeniyle viral, fungal ve bakteriyel enfeksiyonlara sık rastlanmaktadır. Listeria monocytogenes makrofaj ve epitel hücrelerine yerleşen gram pozitif bir bakteridir. Hücre içinde çoğalması nedeniyle konak savunmasında bakterinin virü-lansının yanısıra konağın bağışıklık sistemi de önemlidir. Hayatı tehdit edici L. monocytogenes infeksiyonlarına ve menenjite özellikle yeni doğan, yaşlılar ve organ nakli yapılmış hastalar da dahil olmak üzere immün sistemi baskılanmış kişilerde sık rastlanmaktadır. Burada, nadir görülmesi nedeniyle, miyelodisplastik sendrom-aşırı blastlı refrakter anemi (MDS-RAEB) tanısı ile allogeneik kemik iliği nakli yapıldıktan altı ay sonra menenjit tablosu ile başvuran ve etken olarak L. monocytogenes gösterilen bir olgu sunduk.

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Listeria monocytogenes infection in patients with cancer

Cited by 60 publications

References 29 publications

Antimicrobial Susceptibilities of Listeria monocytogenes Isolated in Japan

Antimicrobial Susceptibilities of Listeria monocytogenes Isolated in Japan

Important emerging bacterial zoonotic infections affecting the immunocompromised

isteria Monocytogenes Meningitis After Allogeneic Bone Marrow Transplantation in a Patient with Myelodysplastic Syndrome-Refractory Anemia with Excess Blasts: Case Report

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