Listeria endocarditis and spondylodiscitis: A case report and review of the literature

Randrianarisoa, Rova Malala Fandresena; Ramanandafy, Herveat; Mania, Alexandre; Benelhadj, Assia Djelloul; Clément, Melissa; Sabbagh, Lara; Vernet, Pierre; Monjanel, Hélène; Trouillier, S.

doi:10.1002/ccr3.5899

Cited by 3 publications

(2 citation statements)

References 20 publications

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“…Listeriosis is a notifiable disease in Madagascar. A recent study [ 3 ] documented the case of a 75-year-old man with an aortic bioprosthesis, who was admitted with polyarthritis in an afebrile state. Blood cultures confirmed the presence of L. monocytogenes , leading to the diagnosis of Listeria endocarditis and spondylodiscitis, both uncommon manifestations of listeriosis.…”

Section: Introductionmentioning

confidence: 99%

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Clinical and genomic features of a Listeria monocytogenes fatal case of meningitis in Madagascar

Rasoanandrasana,

Rabenandrasana,

Ravaoharisoa

et al. 2024

Access Microbiology

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Listeriosis constitutes a significant public health threat due to its high mortality rate. This study investigates the microbiological and genomic characteristics of Listeria monocytogenes isolates in Madagascar, where listeriosis is a notifiable disease. The analysis focuses on a fatal case of meningeal listeriosis in a 12-year-old child. Genomic analysis revealed a novel cgMLST type (L2-SL8-ST8-CT11697; CC8, serogroup Iia) with typical virulence and antibiotic resistance profiles. These isolates, unique to Madagascar, formed an independent clade in the phylogenetic tree. This study presents the first genomic characterization of Listeria isolates in Madagascar, highlighting the necessity of ongoing genomic surveillance to strengthen listeriosis prevention and control strategies in the region.

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Section: Introductionmentioning

confidence: 99%

“…Blood cultures confirmed the presence of L. monocytogenes , leading to the diagnosis of Listeria endocarditis and spondylodiscitis, both uncommon manifestations of listeriosis. The patient showed improvement following antibiotic therapy [ 3 ]. Here we describe a case of invasive listeriosis at the CHU Befelatanana in Madagascar.…”

Section: Introductionmentioning

confidence: 99%

Clinical and genomic features of a Listeria monocytogenes fatal case of meningitis in Madagascar

Rasoanandrasana,

Rabenandrasana,

Ravaoharisoa

et al. 2024

Access Microbiology

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Listeria endocarditis and spondylodiscitis: A case report and review of the literature

Randrianarisoa¹,

Ramanandafy²,

Mania

et al. 2022

Clinical Case Reports

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Retrospective Investigation of the Whole Genome of the Hypovirulent Listeria monocytogenes Strain of ST201, CC69, Lineage III, Isolated from a Piglet with Fatal Neurolisteriosis

Zaitsev¹,

Khizhnyakova²,

Feodorova³

2022

Microorganisms

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Listeria monocytogenes (Lm), the causative agent for both human and animal listeriosis, is considered to be a rare but potentially fatal foodborne pathogen. While Lm strains associated with current cases of human listeriosis are now being intensely investigated, our knowledge of this microorganism which has caused listerial infection in the past is still extremely limited. The objective of this study was a retrospective whole-genome sequence analysis of the Lm collection strain, 4/52-1953, isolated in the middle of the 20th century from a piglet with listerial neuroinfection. The multi-locus sequence typing (MLST) analysis based on seven housekeeping genes (abcZ, bglA, cat, dapE, dat, ldh, and lhkA) showed that the Lm strain 4/52-1953 was assigned to the sequence type 201 (ST201), clonal complex 69 (CC69), and phylogenetic lineage III. The strain 4/52-1953, similarly to other ST201 strains, probably originated from the ST9, CC69 via ST157. At least eight different STs, ST69, ST72, ST130, ST136, ST148, ST469, ST769, and ST202, were identified as the descendants of the first generation and a single one, ST2290, was proved to be the descendant of the second generation. Among them there were strains either associated with some sporadic cases of human and animal listerial infection in the course of more than 60 years worldwide or isolated from food samples, fish and dairy products, or migratory birds. Phylogenetic analysis based on whole genomes of all the Lm strains available in the NCBI GenBank (n = 256) demonstrated that the strain 4/52-1953 belonged to minor Cluster I, represented by lineage III only, while two other major Clusters, II and III, were formed by lineages I and II. In the genome of the strain 4/52-1953, 41 virulence-associated genes, including the Listeria pathogenicity island 1 (LIPI-1), and LIPI-2 represented by two internalin genes, the inlA and inlB genes, and five genes related to antibiotic resistance, were found. These findings can help to make the emergence of both hyper- and hypovirulent variants, including those bearing antibiotic resistance genes, more visible and aid the aims of molecular epidemiology as well.

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Listeria endocarditis and spondylodiscitis: A case report and review of the literature

Cited by 3 publications

References 20 publications

Clinical and genomic features of a Listeria monocytogenes fatal case of meningitis in Madagascar

Clinical and genomic features of a Listeria monocytogenes fatal case of meningitis in Madagascar

Listeria endocarditis and spondylodiscitis: A case report and review of the literature

Retrospective Investigation of the Whole Genome of the Hypovirulent Listeria monocytogenes Strain of ST201, CC69, Lineage III, Isolated from a Piglet with Fatal Neurolisteriosis

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