Liquid phase microextraction associated with flow injection systems for the spectrometric determination of trace elements

Lemos, Valfredo Azevedo; Oliveira, Rafael Vasconcelos; Santos, Walter Nei Lopes dos; Menezes, Rebeca Moraes; Santos, Laize Vieira; Ferreira, Sérgio L.C.

doi:10.1016/j.trac.2018.11.031

Cited by 30 publications

(7 citation statements)

References 94 publications

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“…Other extraction strategies can replace the traditional liquid–liquid extraction in FIA with some advantages such as the simplification of systems, the avoidance of using toxic solvents, and the improvement of precision, enrichment factors, and other analytical characteristics. Solid‐phase extraction, [ 25 ] liquid‐phase microextraction, [ 26,27 ] and cloud‐point extraction [ 28 ] have been coupled to FIA systems, avoiding the use of large amounts of organic solvents.…”

Section: Strategies Based On the Reagents’ Managementmentioning

confidence: 99%

Strategies to Make Methods Based on Flow Injection Analysis Greener

Bezerra

Santelli

Lemos

et al. 2020

CLEAN Soil Air Water

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The implementation of flow injection analysis (FIA) systems and correlated techniques in the laboratory routine provides an increase of analytical throughput and the reduction of risks of analyte losses and contamination. Naturally, it contributes to the reduction of reagent consumption and minimization of waste generation. This paper presents and discusses an overview of the main strategies adopted to make methods based on FIA systems more environmentally friendly, and offers a review of these methods that covers the period from January 2002 to December 2019. Strategies based on reagent management (adoption of procedures without reagents, replacement of toxic reagents, recycling and reuse of reagents and, use of immobilized reagents), the online waste treatment, and the improvements of FIA systems (flow system configurations that avoid reagent wastage, use of green detectors, automation, and miniaturization) are approached in this perspective.

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Section: Strategies Based On the Reagents’ Managementmentioning

confidence: 99%

Strategies to Make Methods Based on Flow Injection Analysis Greener

Bezerra

Santelli

Lemos

et al. 2020

CLEAN Soil Air Water

Self Cite

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“…Recently, considerable efforts have been devoted to analyzing ultra‐trace targets in microliter samples. [ 5–7 ] Microdroplet extraction with the preponderance of low consumption of organic reagents, high sensitivity and integrating sampling, extraction, and concentration generally occurs at the microdroplet interface formed on the miniaturized channel to achieve the enrichment and extraction of trace targets, which manifests immense potential for drug development, biological purification, environmental monitoring, and food safety. [ 8–15 ]…”

Section: Introductionmentioning

confidence: 99%

“…Recently, considerable efforts have been devoted to analyzing ultra-trace targets in microliter samples. [5][6][7] Microdroplet extraction with the preponderance of low consumption of organic reagents, high sensitivity and integrating sampling, extraction, and concentration generally occurs at the microdroplet interface formed on the miniaturized channel to achieve the enrichment and extraction of trace extraction processes in water and n-octanol solvents respectively. The results exhibited that the single-phase extraction successfully realized the targets quantitative transition from the primitive to another phase, both analytes achieved phase conversion approximate to single-phase and complementary solutes hardly interfered in double-phase extraction.…”

Section: Introductionmentioning

confidence: 99%

Biphasic Microdroplet–Microdroplet Extraction for Ultra‐Trace Enriching Analysis

Zhang

Song

et al. 2022

Adv Materials Inter

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targets, which manifests immense potential for drug development, biological purification, environmental monitoring, and food safety. [8][9][10][11][12][13][14][15] The open-channel microdroplet platform with the characteristics of simple manufacture, no external complicated equipment, low sample consumption, and handy sample manipulation has been applied to cell and drug screening, materials synthesis, environmental monitoring, clinical diagnosis, and high-throughput detection. [16][17][18][19][20][21][22][23] With increasingly diversified and procedural applications, researchers are no longer satisfied with the research in an independent microdroplet, but turn to microdropletmicrodroplet contact, fusion, and information communication including aqueous two-phase detection, cell fusion, reactorcomparting, and so on. [24][25][26][27][28][29][30] Currently, the microdroplet-microdroplet research is overwhelmingly based on a single aqueous phase, which has certain limitations for low aqueous-soluble substances, complex sample matrix, and anisotropy research. The biphasic microdroplet-microdroplet system with a uniform overall microdroplet environment and double-phase microdroplet-microdroplet interface can realize interface reaction, information transmission, and material exchange. [31][32][33][34][35] For these reasons, it is imperative to develop a biphasic microdroplet-microdroplet platform, which will enormously broaden the applications of open-channel microdroplet, including liquid-phase microextraction, nanoparticle interface assembly, targeted drug delivery, and high-throughput screening, medical diagnosis, and molecular imaging. [36][37][38][39][40] Here, we demonstrated a 1H,1H,2H,2H-perfluorodecyltrichlorosilane (PFTS)/n-butyl cyanoacrylate (n-BCA) modified mini-pillar platform for biphasic (aqueous and organic) microdroplet-microdroplet enrichment and extraction. PFTS was uniformly bonded by n-BCA (adhesive) to polydimethylsiloxane (PDMS) mini-pillar prepared by template casting method. After coating, the mini-pillar surface displayed multilayer concave microstructure with ultralow surface energy, which enhanced the surface hydrophobicity and from lipophilicity to oleophobicity so that it can compatible with biphasic reagents persistently despite rotation and inversion. The microdropletsmicrodroplets array was subsequently established based on the platform and the applicable extraction parameters for implementing highly efficient biphasic extraction were evaluated. As a proof-of-concept, we achieved extraction analysis of multiple analytes in single-phase, double-phase, and enrichment Enriching trace targets from trace samples is essential for analytical chemistry. Here, a mini-pillar platform for biphasic (aqueous and organic) microdroplet-microdroplet extraction for enrichment analysis is demonstrated. Such mini-pillars with biphasic hydrophobicity can anchor the biphasic microdroplets (organic or aqueous) regardless of rotation and inversion. Methylene blue (MB) and Nile red (NR) are extracted and analy...

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“…Besides, the sample preparation methods can convert samples to a proper form for the instruments. Hollow fiber-liquid phase microextraction (HF-LPME) is a comment sample preparation method utilized for preconcentrating and cleaning various analytes from real samples [17]. HF-LPME is usually performed in two-phase (2-phase-HF-LPME) or three-phase (3-phase-HF-LPME) modes.…”

Section: Introductionmentioning

confidence: 99%

Preconcentration and determination of five antidepressants from human milk and urine samples by stir bar filled magnetic ionic liquids using liquid–liquid–liquid microextraction‐high‐performance liquid chromatography

Taghizadeh

Ebrahimi

Fooladi³

et al. 2022

J of Separation Science

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A sensitive and straightforward liquid-liquid-liquid microextraction method was developed to preconcentrate and cleanup antidepressants, including mirtazapine, venlafaxine, escitalopram, fluoxetine, and fluvoxamine, from biological samples before analyzing with high-performance liquid chromatography. The essential novelty of this study is using magnetic ionic liquids as the extraction phase in the lumen of hollow fiber and preparing a liquid magnetic stir bar. In this method, polypropylene hollow fiber was utilized as the permeable membrane for the analyte extraction. Six magnetic ionic liquids consisting of the transition metal and rare earth compounds were synthesized and then hollow fiber lumen was injected as acceptor phase to extract the antidepressants. Besides, 3-pentanol as a water-immiscible solvent was impregnated in the hollow fiber wall pores. The effective factors in the method were optimized with the central composition design. The resultant calibration curves were linear over the concentration range of 0.8-400.0 ng mL −1 (R 2 ≥ 0.996). The method displayed the proper detection limit (0.11-0.24 ng mL −1 ), the reasonable limit of quantification (≤0.79 ng mL −1 ), wide linear ranges, high preconcentration factors (≥294.3), and suitable relative standard deviation (2.31-5.47%) for measuring antidepressant medications. Analysis of human milk and urine samples showed acceptable recoveries of 96.5-103.8% with excellent relative standard deviations lower than 5.95%.

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Liquid phase microextraction associated with flow injection systems for the spectrometric determination of trace elements

Cited by 30 publications

References 94 publications

Strategies to Make Methods Based on Flow Injection Analysis Greener

Strategies to Make Methods Based on Flow Injection Analysis Greener

Biphasic Microdroplet–Microdroplet Extraction for Ultra‐Trace Enriching Analysis

Preconcentration and determination of five antidepressants from human milk and urine samples by stir bar filled magnetic ionic liquids using liquid–liquid–liquid microextraction‐high‐performance liquid chromatography

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