Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application

Abstract

Although vascular stents have been widely used in clinical practice, there is still a risk of in-stent restenosis after their implantation. Combining conventional vascular stents with liquid metal-based electrodes with impedance detection, irreversible electroporation, and blood pressure detection provides a new direction to completely solve the restenosis problem. Compared with conventional rigid electrodes, liquid metal-based electrodes combine high conductivity and stretchability, and are more compliant with the implantation process of vascular stents and remain in the vasculature for a long period of time. This perspective reviews the types and development of conventional vascular stents and proposes a novel stent that integrates liquid metal-based electrodes on conventional vascular stents. This vascular stent has three major functions of prediction, detection and treatment, and is expected to be a new generation of cardiovascular implant with intelligent sensing and real-time monitoring.

Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease

“…In cardiovascular diseases (CVDs), plaque accumulates in the coronary artery and affects blood flow, − resulting in a lack of oxygen or nutrition in the heart that can lead to death. The American Heart Association annually releases statistical reports on heart disease, stroke, and cardiovascular risk factors, and considerable research efforts are devoted to CVD. , This focus includes artificial polymer bypass graft transplants, ,− stent material innovations, antithrombosis medicine studies, ,− tissue engineering for artificial vascular grafts, ,, tissue repair medicine for ischemia, ,− and creating biomarkers for detection. ,,, …”