“…Aqueous two-phase systems (ATPS) are used extensively in bioseparation processes, − nanomaterials separations, − and other synthetic processes . Within ATPS, organic–inorganic systems such as polymer–salt systems have been shown to phase separate into an organic-rich phase and an organic-poor phase at high concentrations. − This is likely to occur in situations in which concentrated salt solutions contain organics such as oil recovery, − oil spill cleanup, , and even water droplets in the atmosphere. − These systems exhibit liquid–liquid phase separation, the composition of which is dependent on a number of system parameters including the chemical composition of the organic and inorganic, ,, the molecular weight of the organic molecule, , and the temperature of the system. ,, Mapping out the phase behavior in three-component systems (solvent, organic, and salt) is complicated by this large parameter space, both experimentally and theoretically. In addition, prediction of the thermodynamics of ionic species and larger molecular weight organics is complex and rarely at a level capable of predicting liquid–liquid extraction behavior.…”