Liquid crystals as optical amplifiers for bacterial detection

Zafiu, Christian; Hussain, Zakir; Küpcü, Seta; Masutani, Akira; Kılıçkıran, Pınar; Sinner, Eva‐Kathrin

doi:10.1016/j.bios.2016.01.017

Cited by 36 publications

(30 citation statements)

References 28 publications

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“…[ 15–21 ] Regarding biosensors, the concept involves either the imaging of targeted species displayed at solid surfaces, or sensing at LC/aqueous interfaces (LC thin films or droplets). So far, LC‐based biosensors have been reported to detect a wide range of biomolecules such as glucose, [ 22 ] cholesterol, [ 23 ] lipids, [ 24 ] antimicrobial peptides, [ 25 ] proteins, [ 26,27 ] antigens, [ 28 ] pathogen DNA, [ 29 ] viruses, [ 30 ] bacteria, [ 31 ] or mammalian cells. [ 32,33 ] Nonetheless, the exploitation of LCs in biosensing devices has already been reviewed by other authors [ 16,19 ] and is outside the scope of this work.…”

Section: Introductionmentioning

confidence: 99%

Seeing the Unseen: The Role of Liquid Crystals in Gas‐Sensing Technologies

Esteves

Ramou

Porteira

et al. 2020

Advanced Optical Materials

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Fast, real‐time detection of gases and volatile organic compounds (VOCs) is an emerging research field relevant to most aspects of modern society, from households to health facilities, industrial units, and military environments. Sensor features such as high sensitivity, selectivity, fast response, and low energy consumption are essential. Liquid crystal (LC)‐based sensors fulfill these requirements due to their chemical diversity, inherent self‐assembly potential, and reversible molecular order, resulting in tunable stimuli‐responsive soft materials. Sensing platforms utilizing thermotropic uniaxial systems—nematic and smectic—that exploit not only interfacial phenomena, but also changes in the LC bulk, are demonstrated. Special focus is given to the different interaction mechanisms and tuned selectivity toward gas and VOC analytes. Furthermore, the different experimental methods used to transduce the presence of chemical analytes into macroscopic signals are discussed and detailed examples are provided. Future perspectives and trends in the field, in particular the opportunities for LC‐based advanced materials in artificial olfaction, are also discussed.

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Section: Introductionmentioning

confidence: 99%

Seeing the Unseen: The Role of Liquid Crystals in Gas‐Sensing Technologies

Esteves

Ramou

Porteira

et al. 2020

Advanced Optical Materials

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“…Thus, biomimetic liquid crystal sensors are ideal for measuring the antibiotic susceptibility of Salmonella and other pathogenic species at various temperatures. Consequently, many groups are developing such devices for the detection of food pathogens [91], including Salmonella. This impetus has already led to the fruition of several commercial liquid crystal sensors, such as the Crystal Diagnostics Xpress System ® (CDx) (Crystal Diagnostics Ltd., Broomfield, CO, USA), which has recently received multiple AOAC accreditations from the FDA.…”

Section: Optical Biosensorsmentioning

confidence: 99%

Recent Advances in the Detection of Antibiotic and Multi-Drug Resistant Salmonella: An Update

Hulme

2021

IJMS

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Antibiotic and multi-drug resistant (MDR) Salmonella poses a significant threat to public health due to its ability to colonize animals (cold and warm-blooded) and contaminate freshwater supplies. Monitoring antibiotic resistant Salmonella is traditionally costly, involving the application of phenotypic and genotypic tests over several days. However, with the introduction of cheaper semi-automated devices in the last decade, strain detection and identification times have significantly fallen. This, in turn, has led to efficiently regulated food production systems and further reductions in food safety hazards. This review highlights current and emerging technologies used in the detection of antibiotic resistant and MDR Salmonella.

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“…Similarly, Zafiu [38] reported a method for the detection of bacteria by utilizing the interaction of lipopolysaccharides (PPS) with liquid crystals, visualized in an LC-based sensing system. This LPS/LC combination as a sensing layer could interact with three different bacterial species, and the presence of bacteria was detected regardless of their viability with high sensitivity (minimum of 500 cells mL −1 ) and high efficiency (maximum detection time, 15 min).…”

Section: Cancer Cell Diagnosis and Detection Of Virus And Bacteriamentioning

confidence: 99%

Application and Technique of Liquid Crystal-Based Biosensors

Luan

Luo

2020

Micromachines

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Liquid crystal biosensors are based on changes in the orientation of liquid crystal molecules induced by specific bonding events of biomolecules. These biosensors are expected to serve as a promising system to detect biomolecules, biomolecular activity, and even small chemical molecules because they are inexpensive, sensitive, simple, effective, and portable. Herein, we introduce the principle and fabrication of liquid crystal biosensors and review the research progress in signal-amplified technology for liquid crystal sensing and its application in the detection of viruses, bacteria, proteins, nucleic acids, and small chemical molecules. In addition, the current theoretical and practical issues related to liquid crystal biosensors were investigated.

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Liquid crystals as optical amplifiers for bacterial detection

Cited by 36 publications

References 28 publications

Seeing the Unseen: The Role of Liquid Crystals in Gas‐Sensing Technologies

Seeing the Unseen: The Role of Liquid Crystals in Gas‐Sensing Technologies

Recent Advances in the Detection of Antibiotic and Multi-Drug Resistant Salmonella: An Update

Application and Technique of Liquid Crystal-Based Biosensors

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