Liquid crystal-based sensors for the detection of heavy metals using surface-immobilized urease

Hu, Qiongzheng; Jang, Chang‐Hyun

doi:10.1016/j.colsurfb.2011.07.052

Cited by 81 publications

(43 citation statements)

References 22 publications

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“…It has been reported that metal ions affect orientations of LC under several possible mechanisms [9,[27][28][29]. To better understand this phenomenon, droplets of sodium chloride solution (0.5 M) were dispensed onto three types of surfaces.…”

Section: Effect Of Sodium Chloride On Orientations Of Lcsmentioning

confidence: 99%

“…For example, Abbott's group reported LC sensors for detecting peptides, lipids and other chemical compounds [2][3][4][5][6][7]. Other groups also developed a series of LC sensors for the detection of DNA, proteins and small molecules including thiol, amines and metal ions [8][9][10][11]. An interesting observation arising from these studies is that when a thin layer of LC is in contact with a liquid or a solid interface, the orientation of LC becomes very sensitive to ionic species (proton, electrolytes, and metal ions) present at the interface [12][13][14].…”

Section: Introductionmentioning

confidence: 97%

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Applications of metal ions and liquid crystals for multiplex detection of DNA

Liu

Yang

2015

Journal of Colloid and Interface Science

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Section: Effect Of Sodium Chloride On Orientations Of Lcsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

Applications of metal ions and liquid crystals for multiplex detection of DNA

Liu

Yang

2015

Journal of Colloid and Interface Science

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“…Helicobacter pylori (Hp) and Escherichia coli (E. coli) based on pH changes of the aqueous solution 41,42. In consideration of the sensitive pH responses of the fabricated Eu-POM/IL supramolecular spheres, we developed a simple and convenient approach with dual responses of turbidimetric and fluorescent signaling for the detection of urease.…”

mentioning

confidence: 99%

Stimuli-Responsive Polyoxometalate/Ionic Liquid Supramolecular Spheres: Fabrication, Characterization, and Biological Applications

Gong

Wang

et al. 2016

Langmuir

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We report fabrication, characterization, and potential applications of polyoxometalate (POM)/ionic liquid (IL) supramolecular spheres in water for the first time. These supramolecular spheres have highly ordered structures and show excellent reversible self-assembly and tunable photoluminescence properties, which can be manipulated by adjusting pH of the aqueous solution. Specifically, the formation of POM/IL supramolecular spheres results in quenching of fluorescence emitted by Eu-POM because hopping of the d1 electron in the POM molecule is blocked by hydrogen bond existing between the oxygen atom of POM and the carboxylic acid group of IL. However, the fluorescence can be completely recovered by gradually increasing pH of the aqueous solution due to the pH-induced deprotonation of the carboxylic acid group of IL, which results in disassembly of the fabricated supramolecular spheres. Applications of these stimuli-responsive photoluminescent POM-based supramolecular materials are demonstrated in biological media. Dual signaling responses of turbidity and fluorescence are observed simultaneously in the detection of urease and heavy metals based on pH-induced disassembly of the supramolecular spheres during the biochemical events in aqueous solution. In addition, guest molecules are encapsulated into the supramolecular spheres, and controlled release of these entrapped molecules is demonstrated in the presence of external stimuli. This study shows potential of stimuli-responsive POM/IL supramolecular materials in biological applications.

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“…Gani et al (2010) developed PVCsolgel immobilized urease-based optical biosensor, but did not investigate lead effect. A liquid crystal (LC) based optical biosensor has also been reported by Hu and Jang (2011). The inadequacy with all these studies was the unaddressed issue of lead specificity and application on complex samples as milk.…”

Section: Introductionmentioning

confidence: 99%