Liquid chromatographic determination of folic acid in multivitamin-mineral preparations

Development of a highly sensitive and selective hyphenated technique (molecularly imprinted micro-solid phase extraction fiber–molecularly imprinted polymer fiber sensor) for ultratrace analysis of folic acid

“…Majority of the reported papers are based on chemically modified electrodes which are very tedious, more time consuming, and detection limits were not more than 0.1015 ng mL −1 [15]. Insofar as capillary electrophoresis [23,24,52], ion-pair-RP-HPLC-SPE [53], ion-pair-RP-HPLC-UV [54], HPLC-Microbiological assay [55], and LC-determination of FA [56] are concerned, the reported sensitivities were not less than 0.90 ng mL −1 . The proposed MIM-SPE fiber-MIP-fiber sensor is, thus, compared with a highly sensitive differential pulse adsorptive stripping voltammetry (DPAdSV) method on calixarene-based chemically modified electrodes (CMEs) [8] using Student's t-test (t cal < t tab , confidence level 95%, r = 0.99, Table 1).…”

Effect of graphite oxide and exfoliated graphite oxide as a modifier for the voltametric determination of dopamine in presence of uric acid and folic acid

“…This vitamin is essential for rapid cell growth like blood production, especially during pregnancy. The deficiency of FA can cause health problems 33 , 34 . Methods like chromatography 35 , 36 , flow-injection chemiluminometry 37 , and Spectrophotometry 38 can be used to detect FA.…”

Electrochemical determination of ascorbic acid, uric acid and folic acid using carbon paste electrode modified with novel synthesized ferrocene derivative and core–shell magnetic nanoparticles in aqueous media

“…[7][8][9] UA is the naturally occurring end product of purine metabolism, whose level disorder is associated with various diseases, including gout, hyperpiesia and Lesch-Nyhan syndrome, [10] indicating the importance of UA measurements in biological fluids as a marked sign in the onset of such disorders. [14] FA levels are currently measured by liquid chromatography, [15,16] flow-injection chemiluminometry, [17] isotope dilution-liquid chromatography/tandem mass spectrometry [18] and spectrophotometric methods. [11,12] Obtaining precise UA concentrations using colorimetric methods and enzymatic procedures is unreliable due to their high selectivity and high cost.…”

“…Based on reports, reduced folate level can lead to development of carcinogenesis because FA coupled with vitamin B 12 is involved in nucleotide synthesis, cell division and gene expression. [14] FA levels are currently measured by liquid chromatography, [15,16] flow-injection chemiluminometry, [17] isotope dilution-liquid chromatography/tandem mass spectrometry [18] and spectrophotometric methods. [19] Several electrochemical methods have been developed for measuring FA levels because of the electroactive nature of FA.…”