Electrochemical determination of ascorbic acid, uric acid and folic acid using carbon paste electrode modified with novel synthesized ferrocene derivative and core–shell magnetic nanoparticles in aqueous media

Abstract

2-(4-Ferrocenyl-1,2,3-triazol-1-yl)-1-(naphthalen-2-yl)ethanone (2FTNE) and magnetic core-shell manganese ferrite nanoparticles (CMNP) were fabricated and applied to produce a modified carbon paste electrode (CPE). The electrochemical behaviour of ascorbic acid (AA) was investigated using cyclic voltammetry and measured by square wave voltammetry along with that of uric acid (UA) and folic acid (FA). The 2FTNECMNP-modified CPE (2FTNECMNPPE) had electrocatalytic activity towards AA oxidation that was greater than that of bare CPE and CMNP-modified CPE. Based on the results, the linear oxidation peak current was 0.01-60 μM for AA level and the correlation coefficient was 0.9997. According to three times the standard deviation for the blank, the limit of detection was calculated as 0.002 μM. Our results showed an increase in selectivity, stability and reproducibility for 2FTNECMNPPE, which significantly could measure AA, UA and FA levels in AA ampoule, FA tablet and urine samples. It can be concluded that 2FTNECMNPPE has promising capacity in the development of electrochemical sensors.

A Novel Electrochemical Sensor for Detection of Nicotine in Tobacco Products Based on Graphene Oxide Nanosheets Conjugated with (1,2-Naphthoquinone-4-Sulphonic Acid) Modified Glassy Carbon Electrode

“…The results illustrated the reproducible reaction with both anodic and cathodic peaks, observed at potentials 0.25 and −0.11 V. Additionally, by increasing the number of cycles, the continuous growth of Nq film was obtained. The peak separation potential ΔE p = (E pa − E pc ) was calculated to be 0.36 V (was higher than 0.059 V) as expected for a quasi-reversible system [ 48 ]. Then, the Nq/GCE behavior in 0.10 M PBS (pH 7.0) was examined under various scan rates ranging from 25 to 500 mV/s, as displayed in Figure 6 .…”

Confinement Catalysis of Non‐covalently Functionalized Carbon Nanotube in Ascorbic Acid Sensing

“…Where C 0 is the concentration of the AA, n is a number of electrons involved in the oxidation (n = 2), and α is transfer coefficient (0.5) [70][71][72]. The calculated D value for irreversible oxidation of AA is 2.96 � 0.18 × 10 À 5 cm 2 s À 1 .…”

Ultrasensitive multiwall carbon nanotube-mesoporous MCM-41 hybrid-based platform for the electrochemical detection of ascorbic acid

“…32–34 Among them, the electrochemical sensing remains as a simple cost-effective alternative that also offers high sensitivity, reliability and reproducibility. 31,35–38…”

“…[32][33][34] Among them, the electrochemical sensing remains as a simple cost-effective alternative that also offers high sensitivity, reliability and reproducibility. 31,[35][36][37][38] In this context, we report for the first time the optimization of MWCNT-MCM-41 hybrid preparation through an experimental design based on Central Composite Design (CCD)/ Response Surface Methodology (RSM). 39 RSM is a collection of statistical and mathematical techniques helpful for developing, improving, and optimizing processes.…”