Liquid-based cytology aids in primary fallopian tube cancer diagnosis

Abstract

Primary fallopian tube carcinoma (PFTC) is a rare malignant carcinoma among all genital tract malignancies. It occurs most commonly in postmenopausal women and is similar to ovarian malignancy historically and clinically. Because of its insidious onset and silent course, the diagnosis is made usually postoperatively. Liquid-based cytology (LBC) is a type of method for cervical cancer screening, but sometimes it may aid in making PFTC diagnosis. We report a 47-year-old woman with PFTC, whose diagnosis was made with the aid of LBC.

Bilateral Fallopian Tube Adenocarcinoma

“…However, it has been reported in young girls aged 17-19yrs. [6,7] In the present case the woman was 49 year old. The features considered pathognomonic of hydrops tubae profluens are intermittent discharge of clear or bloody fluid, either spontaneous or caused by pressure, followed by shrinkage of the adnexal mass.…”

“…[2] Nulliparous women are at a higher risk for developing primary fallopian tube carcinoma (PFTC) with parity being strongly protective. [6] PFTC most frequently occurs in postmenopausal women between the fourth and sixth decades of life, with a median age of 55 years. However, it has been reported in young girls aged 17-19yrs.…”

“…[5] Ren et al suggested that the finding of dyskeratotic glandular cells on cervical smear should alert one regarding the possibility of fallopian tube carcinoma although these cells are seen in ovarian, serous and primary peritoneal carcinomas. [6] Resemblance to the ovarian carcinomas makes diagnosis challenging and even difficult.…”

Redesigning the Apparel Product Development Process Based on the No-Interval Coherently Phased Product Development Model

“…The synergy of different divisions that share the responsibility and risk for producing a quality product is necessary to successfully meet and interpret the ever-changing demands of the consumer [7]. In practice many activities of the product development process are carried out simultaneously and interaction will be common.Compared to the sequential process, simultaneous phases of development reduce time to market and smooth the transition between phases.…”