Bilateral Fallopian Tube Adenocarcinoma

Abstract

Primary fallopian tube carcinoma [PFTC] is an uncommon, aggressive neoplasm. Diagnosis is based on ultrasonographic findings combined with a thorough histopathological examination. It must be considered as a differential diagnosis in patients presenting with vaginal bleed or discharge, with bilateral adnexal masses and those who fail to respond to antibiotic therapy and drainage. Tubal tuberculosis and trauma have been considered by some to be carcinogenic factors inducing multifocal tumorigenesis of the müllerian duct. Fallopian tube carcinoma being included as part of the cancer spectrum associated with inherited BRCA mutations. We present here a rare case report of a 49yr old lady who came with complains of white discharge per vagina of 6 months duration and underwent bilateral salpingo-oophorectomy, in view of nodular echogenic lesions in the bilateral adnexa on ultrasonography. A diagnosis of primary serous adenocarcinoma -FIGO Stage IC was rendered after histopathological examination. It is important to note that metastasis to the tube is often bilateral in majority of the cases. Primary uterine and ovarian malignancies need to be excluded as in the present case.