Liposomes, Dendrimers and other Polymeric Nanoparticles for Targeted Delivery of Anticancer Agents – A Comparative Study

Abstract

The sections in this article are Introduction Cancer Chemotherapy: so Far, but not so Good Nanoparticles and Drug Delivery in Cancer: a new Road Importance of Nanoparticles in Cancer Therapy An Overview of Targeting Methods Means to the End: Methods for Targeting Passive Targeting Magnetic Targeting of Nanoparticles Ligands for Active Targeting Monoclonal Antibodies against Tumor‐specific Antigens Targeting the Angiogenic Process Folic Acid and Cancer Targeting Transferrin as a Targeting Ligand Other Targeting Ligands Targeting with Different Types of Nanoparticles Liposomes in Cancer Targeting Beyond Immunoliposomes Dendrimers Other Polymeric Nanoparticles Conclusion

The ‘timely’ development of Rexin-G: First targeted injectable gene vector (Review)

“…The review assumes a posture of the medical avant-garde, but does not assume that the reader is either a molecular, genetic, or biotechnological cognoscente. The subject matter addressed herein is necessarily focused on very recent developments in the field, while pertinent background material on applied nanotechnology (2,3), gene delivery vehicles (4)(5)(6), cell cycle control (7,8), virotherapy (9,10) and tumor targeting technologies (11)(12)(13)(14)(15), as well as early clinical trials of Rexin-G (16)(17)(18) and associated histopathology (19) are available in the existing literature. The text is divided into discrete subsections in which critical distinctions are made and considered opinions are presented, in a strategic flow of contextual information that travels from the theoretical to the clinical to the analytical and beyond, to the evolving praxis of modern medicine.…”