Liposomes: A Novel Drug Delivery System: An Overview

Nikam, Nikita R.; Patil, Prashant; Vakhariya, Rohan R.; Magdum, C. S.

doi:10.5958/2231-5691.2020.00005.2

Cited by 28 publications

(14 citation statements)

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“…For example, unsaturated phosphatidylcholine originates from a natural source that is less stable but more permeable. Long acyl chains produce a hard, impermeable bilayer structure in the saturated ones, such as dipalmitoyl phosphatidylcholine [89].…”

Section: Liposomesmentioning

confidence: 99%

Functional Nanostructured Materials in the Cosmetics Industry: A Review

et al. 2023

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Cosmetics have always been in demand across the globe among people of all age groups. In the modern cosmetic world, nanostructured materials have proven hugely advantageous in producing cosmeceuticals or ‘nano-cosmeceuticals’ and various beauty products. The application of nanostructured materials in cosmetic products possesses some challenges in terms of short- and long-term safety and environmental issues, despite their growing popularity. The nanostructured particles in cosmeceuticals provide a targeted route of administration due to their high penetrability, site selectivity, high effectiveness, prolonged activity, and drug encapsulation potential. However, standard methods for toxicity evaluation may not be relevant for cosmeceuticals, leading to the need for an alternative methodology. This review article compiles detailed descriptions of all significant aspects of nanostructured materials in the cosmetics industry, which include the synthesis and characterization of relevant nanostructured materials for cosmeceuticals, state-of-the-art practices, mechanisms for the synthesis of advanced materials, toxicological concerns in terms of health risks in humans, and environmental concerns. Also, a proposal for new approaches in terms of regulatory measures to mitigate these problems has been suggested. The primary focus of this article is to provide a comprehensive outlook on this subject area and contribute to the exploration of new prospects and emerging roles of nanostructured materials in the cosmetics industry.

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Section: Liposomesmentioning

confidence: 99%

Functional Nanostructured Materials in the Cosmetics Industry: A Review

et al. 2023

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“…Synthetic polymeric microspheres are widely used in clinical applications, as well as bulking agents, fillers, embolic particles, drug delivery vehicles, and other applications, and have been shown to be safe and biocompatible [15]. However, the main downside of these microspheres is that they have a tendency to move away from the injection site, posing a risk of embolism and further organ damage.…”

Section: Synthetic Polymeric Microspheresmentioning

confidence: 99%

A review on microsphere for novel drug delivery system

Dhamapurkar¹,

Desai²

2022

World J. Adv. Res. Rev.

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Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 µm. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs at tumor site. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene and genetic materials, safe, targeted and effective in vivo drug delivery and supplements as miniature versions of diseased organ and tissues in the body.

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“…Synthetic polymeric microspheres are widely used in clinical applications, as well as bulking agents, fillers, embolic particles, drug delivery vehicles, and other applications, and have been shown to be safe and biocompatible. 22 However, the main downside of these microspheres is that they have a tendency to move away from the injection site, posing a risk of embolism and further organ damage.…”

Section: Synthetic Polymeric Microspheresmentioning

confidence: 99%

A Novel Drug Delivery System: Review on Microspheres

Raj¹,

Sharma²,

Sharma³

et al. 2021

J. Drug Delivery Ther.

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Microspheres are multiparticulate drug delivery systems that are designed to deliver drugs to a particular location at a fixed rate. Microspheres are free-flowing powders made up of biodegradable proteins or synthetic polymers with particle sizes ranging from 1 to 1000µm. Benefits of the use of microspheres in fields such as drug delivery, bone tissue manufacturing, and the absorption and desorption of contaminants by regeneration. The study shows the method of planning and measurement of microsphere parameters. Microspheres are complex, such as bioadhesive microspheres, polymeric microspheres, magnetic microspheres, floating microspheres, radioactive microspheres. Microspheres may be used in various fields such as cosmetics, oral drug delivery, target drug delivery, ophthalmic drug delivery, gene delivery, and others listed in the study. In order to achieve optimal therapeutic effectiveness, it is important to deliver the agent to the target tissue at an optimum level within the right timeframe, resulting in little toxicity and minimal side effects. There are different approaches to supplying the medicinal drug to the target site in a continuous managed manner. One such strategy is the use of microspheres as drug carriers. In this article, the value of the microsphere is seen as a novel drug delivery carrier to achieve site-specific drug delivery was discussed. Keywords: microspheres, method of preparations, polymer, bioadhesion, types of microspheres

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Liposomes: A Novel Drug Delivery System: An Overview

Cited by 28 publications

References 0 publications

Functional Nanostructured Materials in the Cosmetics Industry: A Review

Functional Nanostructured Materials in the Cosmetics Industry: A Review

A review on microsphere for novel drug delivery system

A Novel Drug Delivery System: Review on Microspheres

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