Liposomal and Phytosomal Formulations

Abstract

Liposomes and phytosomes are kind of nanoparticles (NPs) which serve as an imperative tool for the delivery of various bioactive molecules. The molecules possessing lesser water solubility, bioavailability and retention time are encapsulated into both of these formulations. More specifically, liposomes can encapsulate both hydrophobic as well as hydrophilic molecules. While phytosomes contain only plant-based molecules having poor solubility in biological media like flavanones and terpenes. The various advantages of liposomes and phytosomes like biocompatibility, nontoxicity, ease to administer, decrease in dosage and increase in retention time make them potent vehicles for the drug delivery of various molecules. These nanoformulations find potential applications for delivery of various bioactive molecules, in tissue regeneration and as antimicrobials. This chapter highlights the importance of liposomes and phytosomes, methods of their preparation, mechanism of their action and applications.

Green Intelligent Nanomaterials by Design (Using Nanoparticulate/2D-Materials Building Blocks) Current Developments and Future Trends

“…Features like biocompatibility, nontoxicity, easy to administer, reduced dosage and enhanced retention time of the liposomes and the phytosomes make potent vehicles for drug delivery as discussed [247].…”