Liposclerosing Myxofibrous Tumor of the Cranial Vault: A Case Report

Ploof, Jillian; Shaikh, Hamza; Melli, Jenny; Jour, George; Turtz, Alan

doi:10.1093/neuros/nyy071

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…On T1weighted images, the signal intensity of the lesion was comparable to that of skeletal muscle. On T2-weighted images, the signal intensity is greater than that of fat owing to the presence of myxoid tissue, which can be easily distinguished from intraosseous lipoma (3,4,15). The histological compositions of this tumor are complex and may consist of a variety of histological structures in varying proportions, including lipoma, fibroxanthoma, myxoma, myxofibroma, fibrous tissue, cyst formation, fat necrosis, ischemic bone tissue, and rarely cartilaginous tissue (1,2,4,5,7).…”

Section: Discussionmentioning

confidence: 99%

“…Liposclerosing myxofibrous tumor (LSMFT) was first described by Ragsdale and Sweet in 1986 (1). It is a relatively uncommon benign bone tumor that may arise in the proximal femur and other parts such as the ilium, humerus, tibia, ribs, and skull (1)(2)(3)(4)(5). The condition generally manifests itself around 40 years old, and the reported onset age is between 15 and 80 years old, with no notable gender difference (1)(2)(3)6).…”

Section: Introductionmentioning

confidence: 99%

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Liposclerosing myxofibrous tumor of the distal femur: A case report

Zhang

et al. 2023

Front. Surg.

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IntroductionLiposclerosing myxofibrous tumor (LSMFT) is a rare benign fibro-osseous tumor that most frequently occurs in the proximal femur. The reported literature shows that the proximal femur, ilium, tibia, humerus, rib, and skull have occurred, but so far, the female distal femur has not been characterized in detail. This, we think, is the first single comprehensive case report of the female distal femur. To prevent misdiagnosis and overtreatment of this illness, it is critical for us to continue strengthening our knowledge of it and to add it to the differential diagnosis of the space-occupying lesion of the female distal femur.Case summaryTwo months ago, a 55-year-old female patient was found to have a space-occupying lesion of the left distal femur and the pain symptom was aggravated. She underwent thorough curettage and bone grafting without additional treatment to relieve the current symptoms and determine the nature of the lesion in our hospital. The intraoperative specimens were submitted to the pathology laboratory for analysis, and the result was reported as LSMFT. And six months after the operation, the patient returned to our hospital for another x-ray examination and we found that she had recovered well without any signs of recurrence. The patient self-reported that she had now resumed her daily life without any uncomfortable symptoms.ConclusionThe incidence of LSMFT itself is relatively low, and the occurrence of the distal femur is even rarer. However, it is recommended to add LSMFT into the differential diagnosis of the occupying lesions of the distal femur. Once the diagnosis is made, thorough curettage and bone grafting without additional special treatment can achieve better postoperative outcomes. The patient gave her agreement after learning that information about the case will be submitted for publication.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Liposclerosing myxofibrous tumor of the distal femur: A case report

Zhang

et al. 2023

Front. Surg.

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“…Liposclerosing myxofibrous tumors (LSMFT) are rare, benign fibro-osseous lesions commonly occurring in the femoral intertrochanteric region. It can also be seen occasionally at other sites such as humerus, rib, iliac bone (Kransdorf et al, 1999;Ragsdale, 1993), tibia (Choi et al, 2005;Regado et al, 2016) and skull (Ploof et al, 2018). The reason for this strong predilection is unknown.…”

Section: Discussionmentioning

confidence: 99%

Bone SPECT/CT imaging of a liposclerosing myxofibroid tumor in an unexpected localization

Kampen¹,

Antunovic

Luebke

et al. 2018

European J Hybrid Imaging

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Background: The combination of both functional and morphological information using three-phase bone scintigraphy and tomographic imaging with single photon emission tomography/computed tomography (SPECT/CT) allows precise characterization of most bone lesions. The hybrid imaging is most useful when conventional imaging is equivocal or contraindicated (e.g magnetic resonance imaging (MRI). Case presentation: A 69-year old, male patient with moderate pain in his posterior pelvic region was diagnosed with an unclear tumor of the iliac bone. Conventional radiographs, computed tomography (CT), and MRI imaging were inconclusive to confirm or refute a malignant process. There was no abnormal hyperperfusion on the early images. On the delayed images, moderately increased osteoblastic activity was noted, and the provisional diagnosis was in favor of a benign process. Histopathology confirmed a benign liposclerosing myxofibrous tumor located in the left iliac bone. Conclusion: Bone scan SPECT/CT might (a) help in classifying bone lesions by combining their metabolic and morphological (e.g CT) characteristics and (b), might help in discriminating benign and malignant tumors.

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Liposclerosing Myxofibrous Tumor in a Patient with Prostate Cancer

Barnds

Grote

Mettman

et al. 2019

JBJS Case Connector

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Case: A 64-year-old man diagnosed with prostate cancer was incidentally found to have a lesion in his distal femur. Although initially concerning for metastatic prostate cancer, after biopsy by an orthopaedic oncology specialist, a diagnosis of liposclerosing myxofibrous tumor (LSMFT) was confirmed. The lesion was treated with curettage and demineralized bone matrix grafting with close follow-up. Conclusions: This case report illustrates that LSMFT is not confined to the proximal femur and highlights the differences in radiographic appearance between LSMFT and more common metastatic bone lesions.

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Liposclerosing Myxofibrous Tumor of the Cranial Vault: A Case Report

Abstract: LSMFT is a rare tumor that should remain on the differential for lesions of the calvarium. When diagnosed, this lesion can be removed with the goal of gross total resection and excellent cosmesis can be achieved.

Cited by 3 publications

References 6 publications

Liposclerosing myxofibrous tumor of the distal femur: A case report

Liposclerosing myxofibrous tumor of the distal femur: A case report

Bone SPECT/CT imaging of a liposclerosing myxofibroid tumor in an unexpected localization

Liposclerosing Myxofibrous Tumor in a Patient with Prostate Cancer

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