Abstract:Case:
A 64-year-old man diagnosed with prostate cancer was incidentally found to have a lesion in his distal femur. Although initially concerning for metastatic prostate cancer, after biopsy by an orthopaedic oncology specialist, a diagnosis of liposclerosing myxofibrous tumor (LSMFT) was confirmed. The lesion was treated with curettage and demineralized bone matrix grafting with close follow-up.
Conclusions:
This case report illustrates that LSMFT is n… Show more
“…The histological appearance consists of lobules of mature fat with delicate trabeculae of woven and pre-existing lamellar bone. This lesion may demonstrate fat necrosis, histiocytes and fibrosis but lacks the characteristic constellation of features seen in LSMFT [12,16]. Fat necrosis can be seen in higher-stage lesions of intraosseous lipoma.…”
Section: Discussion and Differential Diagnosismentioning
confidence: 93%
“…FD, this is a benign fibroosseous proliferation that replace the normal bone marrow. This is more frequent in childhood and commonly occurs in the proximal femur [16]. The histological findings show a homogeneous pattern characterized by curved, Chinese character-like bony trabeculae without osteoblastic rim.…”
Section: Discussion and Differential Diagnosismentioning
“…The histological appearance consists of lobules of mature fat with delicate trabeculae of woven and pre-existing lamellar bone. This lesion may demonstrate fat necrosis, histiocytes and fibrosis but lacks the characteristic constellation of features seen in LSMFT [12,16]. Fat necrosis can be seen in higher-stage lesions of intraosseous lipoma.…”
Section: Discussion and Differential Diagnosismentioning
confidence: 93%
“…FD, this is a benign fibroosseous proliferation that replace the normal bone marrow. This is more frequent in childhood and commonly occurs in the proximal femur [16]. The histological findings show a homogeneous pattern characterized by curved, Chinese character-like bony trabeculae without osteoblastic rim.…”
Section: Discussion and Differential Diagnosismentioning
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