Abstract:Advantages of the described method include easy harvesting during conventional machine-assisted liposuction, the possibility of removing undesired bands of fibrous tissue from the graft, and easy passage through a 24-gauge needle. Thus sub- and intradermal augmentation is possible with the same material and syringe.
“…Large grafts exhibit higher rates of liquefaction, necrosis, and cyst formation, while too small a graft volume is associated with resorption [75], [79]. To ensure maximal take, many surgeons practice repeated transfers [3], [79], [80], [81].Fig. 3 a. Autologous fat grafting in secondary breast reconstruction .…”
ObjectiveTo systematically review the procedure, applications, and outcomes of autologous fat grafting, a promising technique with various clinical applications.Patients and methodsLiterature review of publications concerning autologous fat grafting.ResultsSince its introduction, lipofilling has become increasingly popular; however, its results are variable and unpredictable. Several modifications have been made to the procedures of fat harvesting, processing, and injecting. Surgical excision and low negative-pressure aspiration with large-bore cannulas minimize adipocyte damage during fat harvesting. The “wet” method of fat harvesting involves fluid injection at the donor site and facilitates lipoaspiration while minimizing pain and ecchymosis. For fat processing, centrifugation at a low speed is preferable to high-speed centrifugation, gravity separation or filtration. Fat injection at the recipient site should be performed using small-gauge cannulas in a fanning out pattern over multiple sessions, rather than a single session. Fat grafts exhibit not only dermal filler properties but also regenerative potential owing to the presence of stem cells in fat tissue. Thus, the clinical applications of autologous fat grafting include correction of secondary contour defects after breast reconstruction, release of painful scar contractures, and treatment of burn scars and radiodermatitis. Lipofilling is also used in aesthetic surgery, such as facial and hand rejuvenation, augmentation rhinoplasty, and breast and gluteal augmentation. The complications of lipofilling are minimal and include bruising, swelling, pain, infection, necrosis, and calcification.ConclusionsLipofilling is a low-risk procedure that can be used to correct soft-tissue defects in the face, trunk, and extremities, with minimal discomfort for patients.
“…Large grafts exhibit higher rates of liquefaction, necrosis, and cyst formation, while too small a graft volume is associated with resorption [75], [79]. To ensure maximal take, many surgeons practice repeated transfers [3], [79], [80], [81].Fig. 3 a. Autologous fat grafting in secondary breast reconstruction .…”
ObjectiveTo systematically review the procedure, applications, and outcomes of autologous fat grafting, a promising technique with various clinical applications.Patients and methodsLiterature review of publications concerning autologous fat grafting.ResultsSince its introduction, lipofilling has become increasingly popular; however, its results are variable and unpredictable. Several modifications have been made to the procedures of fat harvesting, processing, and injecting. Surgical excision and low negative-pressure aspiration with large-bore cannulas minimize adipocyte damage during fat harvesting. The “wet” method of fat harvesting involves fluid injection at the donor site and facilitates lipoaspiration while minimizing pain and ecchymosis. For fat processing, centrifugation at a low speed is preferable to high-speed centrifugation, gravity separation or filtration. Fat injection at the recipient site should be performed using small-gauge cannulas in a fanning out pattern over multiple sessions, rather than a single session. Fat grafts exhibit not only dermal filler properties but also regenerative potential owing to the presence of stem cells in fat tissue. Thus, the clinical applications of autologous fat grafting include correction of secondary contour defects after breast reconstruction, release of painful scar contractures, and treatment of burn scars and radiodermatitis. Lipofilling is also used in aesthetic surgery, such as facial and hand rejuvenation, augmentation rhinoplasty, and breast and gluteal augmentation. The complications of lipofilling are minimal and include bruising, swelling, pain, infection, necrosis, and calcification.ConclusionsLipofilling is a low-risk procedure that can be used to correct soft-tissue defects in the face, trunk, and extremities, with minimal discomfort for patients.
“…Large grafts exhibit higher rates of liquefaction, necrosis, and cyst formation, while very small grafts tend to be reabsorbed [47], [55]. To ensure maximal take, many surgeons perform repeated transfers [47], [56], [57], [58]. In breast reconstruction surgery, fat transplantation can be used not only to fill atrophic scars but also to reduce scar contracture as a regenerative alternative to other surgical techniques [59].…”
IntroductionThe use of autologous fat transplantation to correct volume and contour defects, scars, and asymmetry after breast cancer surgery has increased over the past 20 years. Many developments and refinements in this technique have taken place in recent years, and several studies of the safety of lipofilling in the breast have been published.Presentation of caseWe performed a literature review of this technique, highlighting the crucial role of lipofilling in breast cancer reconstruction.DiscussionThe efficacy of the fat graft transplantation depends on the experience and the technique used by the surgeon. The ASCs (adipose-derived stem cells) contained in the fat graft has proven to be crucial for breast reconstruction by mean the regeneration of tissue, through the chemotactic, paracrine, and immunomodulatory activities and their in situ differentiation.ConclusionThe role of lipofilling for breast reconstruction could be more significant with the application of the findings of experimental research on tissue engineering and ASCs.
“…Autologous fat transfer (AFT) is widely regarded as an ideal method, addressing both biocompatibility and patient concerns [11]. Neuber [12] was the first to describe it in 1893.…”
Section: Introductionmentioning
confidence: 99%
“…The procedure consists of fat transfer via liposuction and infiltration or implantation into the desired region. It is used in reconstructive and aesthetic surgery for facial and body contouring [11,13], but also in other specialties [14,15]. …”
Various materials have been used for tissue augmentation and for the treatment of rhytids. Autologous fat transfer (AFT) is considered ideal regarding biocompatibility and patient concerns. This study was performed on a series of 215 female patients for face rejuvenation with tumescent technique fat harvesting and saline washing. The study was based on two AFT procedures for each patient. Second treatment was performed at least 1 month after the first operation. Their mean age was 55.5 ± 2.1 years. High-definition photographs in five standard views, front (n = 1), side (n = 2) and oblique of 3/4 (n = 2), were taken for the preoperative morphological study. Aesthetic outcomes were evaluated by the operating surgeon, the patient and an independent dermatologist. Outcomes were evaluated by comparing the preoperative photographs with those taken 1 month after the first procedure and at the end of the 1-year follow-up period. At 12 months all the patients except one noted an improvement. Of these 85.6% (184 patients) were satisfied with the treatment. The operating surgeon and the independent observer noted respectively a sufficient correction in 88.8 and 95.3%. AFT was considered painless by 94.9% and slightly painful by 5.1% of subjects. Fat tissue harvesting by tumescent anesthesia and purification with saline washing enable adipocyte viability to be preserved throughout the procedure and to perform the treatment under local anesthesia.
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