Lipomatous tumors of adrenal gland: A case series of 5 patients and review of the literature

Alkhalifa, Abdullah M; Aldossary, Mohammed Yousef; Abusultan, Ammar; AlQattan, Abdullah Saleh; Alsomali, Mohammed; Alquraish, Fatimah; Alkhaldi, Njoud; Alsaeed, Jamal; Alwosaibei, Abdulaziz; Alqambar, Mohammed; Al-Saif, Osama

doi:10.1016/j.ijscr.2020.01.027

Cited by 7 publications

(7 citation statements)

References 28 publications

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“…In another series, only 5% patients had myelolipoma, which is much less than that observed in our series. 8 However, the incidence of benign pheochromocytoma was comparable (21% vs 38.8%), while none of the patient in their series had Cushing's disease. Similarly, they reported adrenal cyst in 21% patients and adrenal hematoma in 14% patients; however, none of the patients in our series had these conditions.…”

Section: Discussionmentioning

confidence: 87%

Multidisciplinary collaborative approach for management of adrenal tumors: Outcomes of minimally invasive adrenalectomy at a single center

et al. 2020

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Introduction: Laparoscopy is currently the gold standard for the management of adrenal tumors as it is associated with less morbidity. Owing to technological advances, even large adrenal tumors are currently amenable to laparoscopic removal. In this work, we describe our multidisciplinary collaborative approach for management of adrenal tumors at a single center. Material and methods: Between January 2017 and January 2020, 18 patients with adrenal lesions were operated at our center. Five of these patients had incidentalomas. All patients were evaluated in coordination with endocrinologists and anesthetists. All patients underwent transperitoneal laparoscopic adrenalectomy. The surgical complications were classified as per Clavein-Dindo system. All patients with pheochromocytoma and Cushing syndrome were followed up by the endocrinologist for further evaluation and titration of glucocorticoids and antihypertensive medication. Results: Two out of the 18 patients had American Society of Anesthesiologists (ASA) physical status III. Out of the 18 patients, only one required conversion to open surgery. Five patients developed intraoperative hypertensive crisis while three patients developed hypotensive crisis. All patients were ambulated on the first postoperative day and were discharged on the third post operative day. None of the patients developed any major (Clavein-Dindo III–V) intra operative or post operative complications. Conclusion: Laparoscopic adrenalectomy is the procedure of choice for adrenal tumors. A multi-disciplinary approach involving the endocrinologist, anesthesiologist, and laparoscopic surgeon can help achieve favorable outcomes.

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Section: Discussionmentioning

confidence: 87%

Multidisciplinary collaborative approach for management of adrenal tumors: Outcomes of minimally invasive adrenalectomy at a single center

et al. 2020

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“…The laparoscopic operation was once considered contraindicated for adrenal tumors exceeding 5-6 cm (26). However, the laparoscopic approach is being increasingly used and extended for larger-size adrenal tumors, and we found 18 articles published reported 23 cases in recent 10 years (3,4,17,25,(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40). Table 1 provides further details of these reports.…”

Section: Discussionmentioning

confidence: 99%

Case report: Adrenal myelolipoma resected by laparoscopic surgery

Feng

Chen

et al. 2022

Front. Oncol.

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IntroductionAdrenal myelolipomas are benign tumors composed mainly of lipomatous elements with myeloid cells. With the development of medical imaging technology, the detection rate has gradually increased. We report a case of adrenal myelolipoma successfully excised through the laparoscope and reviewed existing literature in recent ten years to summarize the feasibility of the laparoscopic approach for this tumor.Case presentationHerein, we described a case of adrenal myelolipoma resected by laparoscope in a 63-year-old male patient. He did not have any other symptoms except the incidental finding of a left adrenal mass. An abdominal CT examination revealed a mixed-density lesion containing some amount of adipose tissue. In conjunction with the patient’s willingness, we performed a laparoscopic operation to remove the lump. The definite diagnosis was confirmed as an adrenal myelolipoma according to the pathology. The patient recovered well postoperatively and without signs of recurrence at a 5-month follow-up.ConclusionAdrenal myelolipoma is commonly benign, asymptomatic, and hormonal inactivity. A surgical strategy is suggested for high-complication-risk patients. The laparoscopic approach is safe and effective with an obvious advantage over open procedures.

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“…Angiomyolipoma is an extremely uncommon tumor of the adrenal gland, detected incidentally. They are rare lesions, often arising in the kidney, and are part of a group of tumors with a diverse appearance known as tumors of perivascular epithelioid cell origin; extrarenal angiomyolipomas are extremely rare [4,5]. Angiomyolipomas represent the 0.7% of adrenal tumors and the 4% of adrenal lipomatous tumors; they are more frequent in male (3:2) with an average age of 54 years.…”

Section: Discussionmentioning

confidence: 99%