Lipoma of lip with cartilage formation

McAndrew, P G; Js, Greenspan

doi:10.1038/sj.bdj.4803743

Cited by 25 publications

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“…Cases of chondrolipoma of the oral cavity have been observed among patients ranging in age from 2 to 72 years [26,27], and most of the tumors are found in the tongue [3,24,25], as observed in the present study, and in the lower lip [23,26,28]. Osteolipomas, in turn, are characterized by lamellar bone trabeculae scattered among proliferating mature adipocytes [14,23].…”

Section: Discussionmentioning

confidence: 53%

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Juliasse

Nonaka

Pinto

et al. 2009

Eur Arch Otorhinolaryngol

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This study evaluated the clinical and histopathologic aspects of 41 cases of oral lipomas diagnosed in a Brazilian population. All records from patients diagnosed with oral lipoma between 1970 and 2008 were reviewed. Histological sections were evaluated by light microscopy. There was a predominance of females (2.4:1), with a peak incidence between the sixth and seventh decade. The buccal mucosa was the most aVected site (53.7%), followed by the buccal sulcus (14.6%) and tongue (9.8%). Tumor size ranged from 0.5 to 10 cm and the mean reported duration was 48 months. Histologically, the following variants were identiWed: lipoma (41.5%), Wbrolipoma (34.1%), spindle cell lipoma (9.8%), sialolipoma (9.8%), osteolipoma (2.4%), and chondrolipoma (2.4%). Most tumors were well delimited, irrespective of the variant. Lipomas are rare tumors of the oral cavity. The characterization of new variants, such as sialolipomas, and the identiWcation of histological subtypes in already known variants, such as low-fat and fat-free spindle cell lipomas, highlight the importance for careful microscopic evaluation of these tumors, which might be combined with immunohistochemistry in some cases.

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Section: Discussionmentioning

confidence: 53%

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Juliasse

Nonaka

Pinto

et al. 2009

Eur Arch Otorhinolaryngol

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“…According to our review of the English-language literature,which included our cases, 6 cases were described as lipoma with osseous component [5–7, 9, 14, 15], 11 cases as chondroid component [4, 8–13, 16, 17] and 1 case as fibrolipoma with osseous/chondroid components. Our Case 2 is namely the first report of fibrolipoma with osseous/chondroid differentiation.…”

Section: Discussionmentioning

confidence: 99%

Rare Lipomatous Tumors with Osseous and/or Chondroid Differentiation in the Oral Cavity Report of Two Cases and Review of the Literature

Kuyama

Fifita

Komiya

et al. 2009

International Journal of Dentistry

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The purpose of this study was to determine the clinicopathological and immunohistochemical features of lipoma/fibrolipoma with rare occasions as osseous and/or chondroid differentiation in the oral cavity. Two cases of the tumors, who presented with a painless, relatively hard mass on the oral mucosa, were studied. These were consisted of a well-circumscribed mass of fatty tissue with chondroid and significant fibrous component intermixed with the lobules of fat cells with chondroid and woven bone component, respectively. Immunohistochemical study revealed that peripheral spindle cells around chondroid tissue stained diffusely for S-100 α & β and Sox-9, though peripheral spindle cells around osteoid tissue only stained for RUNX-2. According to review of the literature, lipoma/fibrolipoma with osseous and/or chondroid differentiation was 18 cases. Also fibrolipoma with osseous and chondroid differentiation is the first to be reported here. These results indicated that the cartilage/bone is produced by differentiation of undifferentiated mesenchymal cells of stroma.

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“…Chondrolipoma is a rare tumor, usually occurring in the parosteal region. The first case of oral chondrolipoma was reported by McAndrew and Greenspan[ 7 ] in 1976 in a 72-year-old male in lower lip and since then only a handful of cases been reported in oral cavity. Many clinical and histopathological characteristics of chondrolipomas of the oral cavity continue to be poorly understood because of the rarity of this tumor, together with the lack of data in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…[ 5 6 ] As per Pubmed database, till date only 14 cases of chondrolipoma in oral cavity have been reported in English literature. [ 7 8 9 10 11 12 13 14 15 16 17 18 19 ] Herein, we report a case of this rare intraoral variant in a 35-year-old male patient.…”

Section: Introductionmentioning

confidence: 98%

Chondrolipoma: Report of a rare intra oral variant with review of histiogenetic concepts

Raj

Dwivedi

Sah

et al. 2014

J Oral Maxillofac Pathol

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Chondrolipomas are benign mesenchymal tumors characterized by the proliferation of mature adipocytes associated with variable amounts of mature cartilaginous tissue. Herein, we describe a case of chondrolipoma of the tongue in a 35-year-old Indian male. The lesion presented as a nodular, sessile, pink mass on posterio-dorsal surface of left side of the tongue since approximately 20 years. Histopathologically, the mass revealed a well circumscribed, encapsulated proliferation of mature adipocytes with islands of well formed mature cartilaginous tissue. Chondrolipomas are uncommon in the oral cavity, with only 14 cases being reported in the English literature.

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Lipoma of lip with cartilage formation

Cited by 25 publications

References 0 publications

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Rare Lipomatous Tumors with Osseous and/or Chondroid Differentiation in the Oral Cavity Report of Two Cases and Review of the Literature

Chondrolipoma: Report of a rare intra oral variant with review of histiogenetic concepts

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