Lipofuscin in monkey ‘lateral geniculate body’

Hasan, Mahdi; Glees, P.

doi:10.1159/000143913

Cited by 11 publications

(1 citation statement)

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“…Intracellular neuronal fibrils, Golgi apparatus, endoplasmic reticulum, mitochondria and Iysosomes have all been considered as possible precursors of lipofuscin (for a review see Hasan and Glees, 1972). Glees and coworkers (Hasan and Glees, 1973;Gopinath and Glees, 1974;Glees, Spoerri and El-Ghazzawi, 1975) strongly favour the mitochondrial genesis of lipofuscin. The cystic bodies with an inner and outer membranein Figures 3c and 4a may perhaps represent stages in mitochondrial swelling, inclusion into lipofuscin granules and degeneration.…”

Section: Discussionmentioning

confidence: 99%

Lipofuscin in the cerebellar cortex of albino rats: An electron microscopic study

Heinsen

1979

Anat Embryol

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Summary. The ultrastructure of autofluorescent, PAS-positive lipofuscin in Purkinje, granule, Golgi epithelial, basket and stellate, microglial and perivascular cells in the cerebellar cortex of senescent rats is described. The membrane-bounded pigment is composed ofthree elements: 1) electron-lucent homogeneaus droplets, 2) a granular matrix and 3) intensely osmiophilic patches. The proportians ofthese three components vary between cell types and one can grossly differentiate a neuronal and a gliallipofuscin. The lipofuscin granules of stellate and perivscular cells are different from lipofuscin of other cerebellar neurons and glia. lt can be concluded from these morphological observations that each cerebellar cell type has its distinct lipofuscin.

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Section: Discussionmentioning

confidence: 99%