Lipödem - Aktuelles zu einem weitgehend unbekannten Krankheitsbild

Schmeller, W.; Meier-Vollrath, Ilka

doi:10.1055/s-2007-966651

Cited by 23 publications

(35 citation statements)

References 5 publications

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“…Das Lipödem beginnt in der Regel nach der Pubertät, nach einer Schwangerschaft oder in Zusammenhang mit dem Klimakterium. Eine gleichzeitige Adipositas, die aggravierend auf das Beschwerdebild wirkt, findet sich bei 50 % der Lipödempatien-tinnen [14].…”

Section: Lipödem: Definition Pathophysiologie Symptomeunclassified

Wasserstrahlassistierte Liposuktion zur Therapie des Lipödems

Münch¹

2017

J Ästhet Chir

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Section: Lipödem: Definition Pathophysiologie Symptomeunclassified

Wasserstrahlassistierte Liposuktion zur Therapie des Lipödems

Münch¹

2017

J Ästhet Chir

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“…2) Bilateral and symmetrical nature with minimal involvement of the feet, resulting in an ''inverse shouldering'' or ''bracelet" effect at the ankle 3) Minimal pitting edema (non-pitting edema is present) 4) Pain, tenderness, and easy bruising 5) Persistent enlargement despite elevation of the extremities or weight loss 6) Increased vascular fragility; easy bruising Often women note that the lipedema appears or is exacerbated at the time of puberty, pregnancy [118] or menopause suggesting an estrogen component; that few men have this condition except those with hypogonadism or hyperestrogenemia supports this hypothesis.…”

Section: Diagnosismentioning

confidence: 99%

“…Inheritance has been noted up to 60% of people with lipedema [118,123,124] but is likely higher due to under diagnosis. In six families over three generations with lipedema, the inheritance pattern was autosomal dominant with incomplete www.chinaphar.com Herbst KL Acta Pharmacologica Sinica npg penetrance [115] .…”

Section: Inheritance Of Lipedemamentioning

confidence: 99%

Rare adipose disorders (RADs) masquerading as obesity

2012

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Rare adipose disorders (RADs) including multiple symmetric lipomatosis (MSL), lipedema and Dercum's disease (DD) may be misdiagnosed as obesity. Lifestyle changes, such as reduced caloric intake and increased physical activity are standard care for obesity. Although lifestyle changes and bariatric surgery work effectively for the obesity component of RADs, these treatments do not routinely reduce the abnormal subcutaneous adipose tissue (SAT) of RADs. RAD SAT likely results from the growth of a brown stem cell population with secondary lymphatic dysfunction in MSL, or by primary vascular and lymphatic dysfunction in lipedema and DD. People with RADs do not lose SAT from caloric limitation and increased energy expenditure alone. In order to improve recognition of RADs apart from obesity, the diagnostic criteria, histology and pathophysiology of RADs are presented and contrasted to familial partial lipodystrophies, acquired partial lipodystrophies and obesity with which they may be confused. Treatment recommendations focus on evidencebased data and include lymphatic decongestive therapy, medications and supplements that support loss of RAD SAT. Associated RAD conditions including depression, anxiety and pain will improve as healthcare providers learn to identify and adopt alternative treatment regimens for the abnormal SAT component of RADs. Effective dietary and exercise regimens are needed in RAD populations to improve quality of life and construct advanced treatment regimens for future generations.

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“…7-9.7 % of the female population are affected (16). The frequency of lipoedema in specialist lymphology clinics is reported as 8-17 % (2,12,(17)(18).…”

Section: Epidemiologymentioning

confidence: 99%

Treatment of lipoedema using liposuction

Rapprich¹,

Baum²,

Kaak³

et al. 2015

Phlebologie

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SummaryBackground: Lipedema is a painful, genetically induced, abnormal deposition of subcutaneous fat in the extremities of women. The pathogenesis is unknown. Also unknown is the number of women affected in Germany. This study presents the epidemiology of the disease. There are currently two treatment options available: Complex physical decongestive therapy and liposuction. Liposuction is the only method that removes fat permanently. An additional study proves its effectiveness and highlights its vital role as part of a comprehensive treatment concept. Patients and methods: As part of the epidemiological research, all patients of a general practioner were examined for leg problems. The liposuction study included the preand postoperative examination of 85 patients, which was carried out using a questionnaire. Results: Lipedema were diagnosed in 5 % of all patients of the GP practice. In all 85 pa-

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Lipödem - Aktuelles zu einem weitgehend unbekannten Krankheitsbild

Cited by 23 publications

References 5 publications

Wasserstrahlassistierte Liposuktion zur Therapie des Lipödems

Wasserstrahlassistierte Liposuktion zur Therapie des Lipödems

Rare adipose disorders (RADs) masquerading as obesity

Treatment of lipoedema using liposuction

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