Lipids and Fatty Acids of Leptospira Interrogans Serovar Copenhageni Virulent Strain Shibaura

Bacterial membrane lipids: diversity in structures and pathways

“…Among the spirochaetes, the distinct genera present different lipid compositions: Borrelia forms PG, PC and GLs, Treponema forms PG, PE, CL and PC, and Leptospira forms PE, PG, CL and lyso-PE. Bacteria of the genus Leptospira have also been described to form GLs and are predicted to be able to form OLs (Livermore and Johnson 1974;Moribayashi et al 1991;Kent et al 2004;Wang, Scagliotti and Hu 2004;Ostberg et al 2007).…”

Comparison of the fatty acid profiles of Borrelia, Serpulina and Leptospira species

“…Such methods are complex and time-consuming and, by comparison, analysis of FAME profiles is a simpler technique when used in conjunction with the MIDI microbial identification system. The Leptospira have been analysed using fatty acid profiles as a key for their classification (Cacciopuoti et al, 1991 ;Moribayashi et al, 1991). In this study we have used fatty acid profiles to distinguish selected members of the spirochaete family and to investigate the possibility of using the relatedness of profiles as a tool for the classification of borrelias.…”

Characterization of acetyl-CoA and propionyl-CoA carboxylases encoded by <italic>Leptospira interrogans</italic> serovar Lai: an initial biochemical study for leptospiral gluconeogenesis via anaplerotic CO<sub>2</sub> assimilation

“…Basic studies related to the biology of Leptospira have mainly focused on potential virulence factors such as lipopolysaccharide [3][4][5][6][7], dynamics of motility [8][9][10][11][12], and outer-membrane proteins [13][14][15][16][17][18][19][20]. However, the study of its metabolism has been largely limited to those special or unique for the spirochetes, such as the biosynthesis of branch-chain amino acids [21][22][23] and the metabolism of lipids [20,24,25].…”