Lipid-based Janus nanoparticles for pharmaceutical and cosmetic applications: Kinetics and mechanisms of destabilization with time and temperature

Benrabah, L.; Kemel, Kamilia; Twarog, Caroline; Huang, Nicolas; Solgadi, Audrey; Laugel, Cécile; Faivre, Vincent

doi:10.1016/j.colsurfb.2020.111242

Cited by 7 publications

(3 citation statements)

References 14 publications

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“…The ZP indicates the NE surface charge and directly impacts the mucoadhesion due to the interaction with negatively charged mucin present in mucous [ 42 ]. Additionally, ZP values distant from zero prevent the NE coalescence process [ 43 ]. NE-LUT presented ZP of −3.7 mV, while NECh-LUT and NECh presented values of +12.8 and +10.6, respectively.…”

Section: Resultsmentioning

confidence: 99%

Optimized Chitosan-Based Nanoemulsion Improves Luteolin Release

et al. 2023

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Luteolin (LUT) is a flavonoid found in several edible and medicinal plants. It is recognized for its biological activities such as antioxidant, anti-inflammatory, neuroprotective, and antitumor effects. However, the limited water solubility of LUT leads to poor absorption after oral administration. Nanoencapsulation may improve the solubility of LUT. Nanoemulsions (NE) were selected for the encapsulation of LUT due to their biodegradability, stability, and ability to control drug release. In this work, chitosan (Ch)-based NE was developed to encapsulate luteolin (NECh-LUT). A 23 factorial design was built to obtain a formulation with optimized amounts of oil, water, and surfactants. NECh-LUT showed a mean diameter of 67.5 nm, polydispersity index 0.174, zeta potential of +12.8 mV, and encapsulation efficiency of 85.49%. Transmission electron microscopy revealed spherical shape and rheological analysis verified the Newtonian behavior of NECh-LUT. SAXS technique confirmed the bimodal characteristic of NECh-LUT, while stability analysis confirmed NECh-LUT stability when stored at room temperature for up to 30 days. Finally, in vitro release studies showed LUT controlled release up to 72 h, indicating the promising potential of NECh-LUT to be used as novel therapeutic option to treat several disorders.

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Section: Resultsmentioning

confidence: 99%

Optimized Chitosan-Based Nanoemulsion Improves Luteolin Release

et al. 2023

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“…Despite those offered advantages, the nanoemulsion also has a drawback, in which the nanoscale layer deformation caused by the destabilization effect may occur after the nanoemulsion has been established resulting in aggregation, coalescence, flocculation, and sedimentation (Öztürk, 2017;Zambrano-Zaragoza et al, 2018). These defective phenomena are mostly caused by the delinquent movement of nanoparticles, the so-called Brownian motion (Benrabah et al, 2020). Additionally, the incorporation of polymeric nanoparticles has been studied lately due to its better control of releasing the loaded ingredients.…”

Section: Nanostructuring Methodsmentioning

confidence: 99%

Advanced biopolymer‐based edible coating technologies for food preservation and packaging

Wibowo,

Salsabila,

Muna

et al. 2023

Comp Rev Food Sci Food Safe

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Along with the growth of the world's population that reduces the accessibility of arable land and water, demand for food, as the fundamental element of human beings, has been continuously increasing each day. This situation not only becomes a challenge for the modern food chain systems but also affects food availability throughout the world. Edible coating is expected to play a significant role in food preservation and packaging, where this technique can reduce the number of food loss and subsequently ensure more sustainable food and agriculture production through various mechanisms. This review provides comprehensive information related to the currently available advanced technologies of coating applications, which include advanced methods (i.e., nanoscale and multilayer coating methods) and advanced properties (i.e., active, self‐healing, and super hydrophobic coating properties). Furthermore, the benefits and drawbacks of those technologies during their applications on foods are also discussed. For further research, opportunities are foreseen to develop robust edible coating methods by combining multiple advanced technologies for large‐scale and more sustainable industrial production.

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“…The high stability of the combination of nanomaterials and lipid particles with cosmetic components indicates high efficiency. However, the probable risks of this method should not be ignored(Benrabah et al 2020;Khezri et al 2018). Producing nanoparticles using plants (Phyto-metal nano-based particles) is another advantageous method to decrease the toxicity of nanomaterials and their hazardous effects on the body.…”

mentioning

confidence: 99%

Nano-biotechnology, an applicable approach for sustainable future

et al. 2022

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Nanotechnology is one of the most emerging fields of research within recent decades and is based upon the exploitation of nano-sized materials (e.g., nanoparticles, nanotubes, nanomembranes, nanowires, nanofibers and so on) in various operational fields. Nanomaterials have multiple advantages, including high stability, target selectivity, and plasticity. Diverse biotic (e.g., Capsid of viruses and algae) and abiotic (e.g., Carbon, silver, gold and etc.) materials can be utilized in the synthesis process of nanomaterials. "Nanobiotechnology" is the combination of nanotechnology and biotechnology disciplines. Nano-based approaches are developed to improve the traditional biotechnological methods and overcome their limitations, such as the side effects caused by conventional therapies. Several studies have reported that nanobiotechnology has remarkably enhanced the efficiency of various techniques, including drug delivery, water and soil remediation, and enzymatic processes. In this review, techniques that benefit the most from nano-biotechnological approaches, are categorized into four major fields: medical, industrial, agricultural, and environmental.

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Lipid-based Janus nanoparticles for pharmaceutical and cosmetic applications: Kinetics and mechanisms of destabilization with time and temperature

Cited by 7 publications

References 14 publications

Optimized Chitosan-Based Nanoemulsion Improves Luteolin Release

Optimized Chitosan-Based Nanoemulsion Improves Luteolin Release

Advanced biopolymer‐based edible coating technologies for food preservation and packaging

Nano-biotechnology, an applicable approach for sustainable future

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