Liparthroplasty for Thumb Carpometacarpal Joint Osteoarthritis: A Case Series with Median 5 Years of Follow-Up

Abstract

Liparthroplasty has recently been discussed as a promising bridging therapy after failed conservative treatment options to postpone arthroplasty surgery of the thumb carpometacarpal joint as long as possible. The current study investigates the sustainability of this method in seven stage II and twenty-four stage III osteoarthritis patients (twenty-seven female and four male cases). Data were evaluated preinterventionally, six months postinterventionally, and two years postinterventionally, as well as a final follow-up assessment after median 5.1 years. We found a significant reduction of all postinterventional disabilities of the arm, shoulder, and hand (dash) scores and pain levels compared to the ones prior to liparthroplasty. Moreover, we even detected a reduction in both parameters within the postinterventional course, so that the DASH scores of our final investigation were significantly lower than the values after six months. Furthermore, 12 of our 31 cases demanded a surgical conversion due to recurrence of symptoms. A binary regression analysis found smokers to have 11 times higher odds for therapy failure, leading to surgical conversion. Seventeen out of nineteen patients in our final assessment stated that they were pleased with liparthroplasty. Due to favorable mid-term outcomes of 61% of the 31 initially treated patients, we recommend liparthroplasty as a reliable bridging therapy for preserving joint integrity as long as possible, especially in non-smoking patients.

Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee

“…In 2022, the same group published the 5-year results of thumb Liparthroplasty and showed a significant reduction in all post-intervention Disabilities of the Arm, Shoulder and Hand (DASH) scores and pain levels compared with those prior to Liparthroplasty. 35 These data confirm Liparthroplasty as a reliable bridging therapy for preserving joint integrity as long as possible.…”

An Examination of Management Patterns and Perceived Health Status of Patients with Osteoporosis within Bayelsa State

“…These study findings highlight the need for comprehensive interventions that address both medication management adherence and the factors contributing to reduced quality of health status among individuals with osteoporosis. The development of educational programs, follow-up strategies, and alternative dosing regimens may contribute to more effective management and enhanced quality of life for this patient population [13][14][15][16][17][18][19][20][21][22][23][24][25].…”

Joint Preservation in Patients with Grade-IV Osteo-Arthritis of The Knee – 12-Months Results after A Multimodal Approach Using Radiofrequency Ablation and Platelet-Rich-Plasma Supercharged Stem Cell-Rich Fat Graft in 42 Consecutive Patients

“…Froschauer at et al were the first authors describing the technique of liparthroplasty in a series of patients with carpo-metacarpal arthritis [27]. In a recently published case series, the same author reported significant improved disabilities of function of the arm, shoulder, and hand (DASH) score after a median five-years follow-up [29]. Jo et al reported encouraging results after intra-articular injection of adipose-derived mesenchymal stem cells for the treatment of osteo-arthritis of the knee [30].…”