Linking evidence to treatment for denture stomatitis: A meta-analysis of randomized controlled trials

Emami, Elham; Kabawat, Marla; Rompré, Pierre; Feine, Jocelyne S.

doi:10.1016/j.jdent.2013.11.021

Cited by 84 publications

(88 citation statements)

References 47 publications

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“…Oral Candida infections encompass a wide spectrum of clinical entities with various presentations (9). The yeasts penetrate into the epithelial cells, which is facilitated by the production of lipases, and overcome the desquamation of epithelial cells to remain within the cells (2,3).…”

Section: Discussionmentioning

confidence: 99%

“…Bacteria, mechanical microtrauma, and poor denture hygiene are predisposing factors for this disease (2,6). The medical treatment of Candida infection depends on the severity and location of the lesion as well as patient's immune status (6)(7)(8)(9). Treatment of denture stomatitis includes cleaning the dentures, avoiding overnight use of dentures, relining or replacement of prosthesis, and use of topical or systemic antifungal medications.…”

Section: Introductionmentioning

confidence: 99%

“…Polyene agents such as nystatin and amphotericin are remedial treatments for primary oral candidosis (1,9,11). Nystatin binds to ergosterol within the cell membrane of Candida and creates pores in the fungal cell membrane, resulting in leakage of fungal cell contents and potassium ions, which results in cell death (7,12,13).…”

Section: Introductionmentioning

confidence: 99%

“…Nystatin binds to ergosterol within the cell membrane of Candida and creates pores in the fungal cell membrane, resulting in leakage of fungal cell contents and potassium ions, which results in cell death (7,12,13). Polyenes are not absorbed from the gastrointestinal tract, and drug-induced resistance is extremely rare (9,12). However, topical use of nystatin produces an unpleasant taste in the mouth and, if swallowed, can cause symptoms such as nausea, vomiting, and diarrhea.…”

Section: Introductionmentioning

confidence: 99%

“…However, topical use of nystatin produces an unpleasant taste in the mouth and, if swallowed, can cause symptoms such as nausea, vomiting, and diarrhea. Azoles may be systemically used for primary deep candidosis such as denture stomatitis and chronic hyperplastic candidosis; however, one harmful effect of the topical application of azoles is their absorption through the gastrointestinal tract (1)(2)(3)9).…”

Section: Introductionmentioning

confidence: 99%

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In vivo study of antifungal effects of low-molecular-weight chitosan against Candida albicans

Atai

Amini

et al. 2017

J Oral Sci

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This study investigated the antifungal effects of low-molecular-weight chitosan solution onCandida albicans in denture stomatitis in comparison with nystatin suspension. This randomized, singleblind clinical trial included 40 patients diagnosed with denture stomatitis. Patients were divided into two groups, wherein one was treated with chitosan and the other with nystatin for 2 weeks. Changes in the erythematous area were recorded during and after treatment. A palatal smear was obtained for each patient before and after treatment to determine the number of blastospores and mycelia of C. albicans. The results were compared using the MannWhitney U test, revealing that the chitosan solution significantly decreased the erythematous surface area, burning sensation, time required for clinical improvement, and number of blastospores and mycelia. The antifungal efficacy of chitosan along with its inherent biocompatibility makes it a promising candidate for use as an antifungal mouthwash.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In vivo study of antifungal effects of low-molecular-weight chitosan against Candida albicans

Atai

Amini

et al. 2017

J Oral Sci

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Dermatoses of the Oral Cavity and Lips

Scully¹

2016

Rook's Textbook of Dermatology, Ninth Edition

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Oral and labial lesions are usually the result of local disease but may be the early signs of systemic disease, including dermatological disorders, and in some instances may cause the main symptoms. This chapter mainly discusses disorders of the periodontal and mucosal tissues that may be related to skin disease and that may present at a dermatology clinic. It should be borne in mind that the professionals most competent in diagnosing and treating oral diseases are those with formal dental training and who are therefore in a position to understand the full complexities of the region. This chapter is divided into a brief discussion of the biology of the mouth, an overview of the more common signs and symptoms affecting specific oral tissues, discussion of the disorders of the oral mucosa of most relevance to dermatology and a tabulated review of oral manifestations of systemic diseases. Only the more classic oral lesions are illustrated. For reasons of space restrictions, diseases affecting the teeth, salivary glands, jaws or temporomandibular joints are not discussed in any depth.

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Dermatoses of the Oral Cavity and Lips

Carey,

Setterfield

2024

Rook's Textbook of Dermatology

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Linking evidence to treatment for denture stomatitis: A meta-analysis of randomized controlled trials

Cited by 84 publications

References 47 publications

<i>In vivo</i> study of antifungal effects of low-molecular-weight chitosan against <i>Candida albicans </i>

<i>In vivo</i> study of antifungal effects of low-molecular-weight chitosan against <i>Candida albicans </i>

Dermatoses of the Oral Cavity and Lips

Dermatoses of the Oral Cavity and Lips

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