Linkage of LHB and MAG to GPI on sheep Chromosome 14

Sheep linkage mapping: RFLP markers for comparative mapping studies

“…Probes that produced complicated banding patterns or variable minor bands were not studied further. We have obtained previous evidence confirming the identity of the target sequence for the beta subunits of follicle-stimulating hormone (FSHB) and luteinizing hormone (LHB) in similar experiments (Montgomery et al 1990;Penty et al 1995).…”

“…Linkage with RFLP markers was used to assign six of the 19 linkage groups derived from the analysis of microsatellite markers in these half-sib pedigrees (Crawford et al 1994). The inclusion of an RFLP for phosphodiesterase, cyclic GMP (rod receptor), and beta polypeptide (PDEB) on the linkage map for sheep chromosome 6 provides an orientation for the linkage group on the physical map (Montgomery et al 1995).…”

Relationships between the number of immunostaining gonadotropes and the plasma concentrations of gonadotrophins in ewes with and without the FecBB gene

“…The implications from these findings of FecB differences in the plasma concentrations of FSH and LH are that they are inducible by GnRH action and that they are independent of factors secreted by the gonad. Moreover, the effects on pituitary hormone release are specific to GnRH action, since no gene differences are observed with respect to thyroid stimulating hormone (TSH) or growth hormone (GH) after treatment with exogenous thyroid hormone releasing hormone or growth hormone releasing hormone, respectively (McNatty et al, 1994 (Montgomery el al, 1990(Montgomery el al, , 1993Penty et al, 1995 (Montgomery et al, 1990(Montgomery et al, , 1993Fleming et al, 1995). Moreover, it does not influence the median charge or half-life of FSH in intact or ovariectomized ewes (Phillips et al, 1995), the hypothalamic GnRH contents or the pituitary GnRH-binding characteristics (Fleming et al, 1990).…”