Linear Warty Lesions in a Child

Tay, Yong–Kwang; Ong, Biauw Chi

doi:10.1001/archderm.135.12.1543-b

Cited by 8 publications

(10 citation statements)

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“…Though non‐ pathognomonic, the cornoid lamella is the most distinctive feature of the various types of porokeratosis 2 . These varieties include the plaque type originally described by Mibelli 3 (few lesions located on the extremities with a cornoid lamella which could be thick up to 10 mm); the superficial disseminated 4 and superficial actinic 5 forms, the punctate variant of palms and soles 6 and the linear type 7 all sharing similar histopathologic features.…”

Section: Introductionmentioning

confidence: 95%

Dermoscopy for the diagnosis of porokeratosis

Delfino¹,

Argenziano²,

Nino³

2004

Acad Dermatol Venereol

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Section: Introductionmentioning

confidence: 95%

Dermoscopy for the diagnosis of porokeratosis

Delfino¹,

Argenziano²,

Nino³

2004

Acad Dermatol Venereol

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“…Lesions appear as grouped annular keratotic papules and may coalesce into larger plaques with central atrophy and raised peripheral borders. When the trunk is involved, lesions often appear zosteriform 2,3 . In our patient, multiple lesions were grouped and linearly arranged on all of the extremities and distributed in a zosteriform pattern on the trunk.…”

Section: Discussionmentioning

confidence: 51%

“…This includes Bowen's disease, squamous cell carcinoma, and, rarely, basal cell carcinoma. This risk of cancer development does not occur to the same degree in all types of porokeratosis 1,3 . The highest risk of malignant degeneration is in large, long‐standing, or linear lesions.…”

Section: Discussionmentioning

confidence: 96%

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Generalized linear porokeratosis

Derviş

Demirkesen

2006

Int J Dermatology

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A 23-year-old woman was seen for widespread skin lesions present since the age of 2.5 years. Twenty years ago, she developed a brown macular lesion on her right buttock. The lesion became hyperkeratotic and subsequently spread through the posterior aspect of her right leg. It later spread to the right side of the trunk and to the right arm. When she was 9 years old, she developed similar lesions on her left arm and leg. After she was 13 years old, no new skin lesions appeared. There was no family history of similar lesions. On examination, there were numerous linear and whorled, reddish-brown, hyperkeratotic plaques, with central atrophy and raised borders, following Blaschko's lines on all of the extremities. These lesions on the extremities extended to the dorsum of the hands and feet (Fig. 1). She had hyperkeratotic lesions on the pressure points of both of the soles, but no palm involvement. The number of lesions on the right side was greater than that on the left. Reddish-brown annular plaques with central atrophy and raised borders, appearing in zosteriform configuration, and numerous individual 2-3-mm erythematous lichenoid papules were observed on the right side of the thorax and the right inguinal region (Fig. 2). No face, scalp, or mucous membrane involvement was seen. The nails of the second and fifth fingers of the right hand and the nail of the third finger of the left hand showed nail dystrophy with longitudinal ridges and pterygium. All the nails of the right foot and the nails of the first and fifth toes of the left foot showed dystrophic changes with subungual keratosis. The patient was otherwise in good health. Two biopsy specimens taken from a hyperkeratotic plaque and a lichenoid papule showed an epidermal invagination with angulated parakeratotic tier, denoting cornoid lamella. The epidermis just underneath the cornoid lamella displayed vacuolization and the granular layer was absent. The adjacent epidermis was atrophic, and hydropic degeneration within the basal cell layer was seen. In the dermis, a nonspecific, mild, chronic, inflammatory cell infiltrate, telangiectatic vessels, and pigment-laden macrophages were present. These findings were consistent with linear porokeratosis (Fig. 3). Microscopic examinations and mycologic cultures of the nails were negative. We decided to treat our case systemically with retinoids, but the patient refused this therapy. So, topical tretinoin 0.05% was started once a day. A marked improvement was observed in hyperkeratosis through the first 4 weeks of treatment and plateaued at 8 weeks. After 10 weeks, the lesions had almost disappeared. We planned to continue the applications every other day. One year later, she remains stable with application of topical tretinoin 0.05% twice a week and is satisfied with the final appearance. She is under regular follow-up.

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“…They are a cosmetic disability and have a significant risk of developing a superimposed cutaneous malignancy. The clinical differential diagnosis includes linear annular lichen planus, linear verrucous epidermal nevus, and lichen striatus (4). Histopathologically, the presence of a cornoid lamella is pathognomonic.…”

Section: Discussionmentioning

confidence: 99%

Unilateral Linear Annular Lesions in a Child

Palit

Inamadar

Yelikar³

2004

Pediatric Dermatology

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An 11-year-old girl presented with hyperpigmented papules and plaques on her left lower limb arranged in a linear pattern. The initial lesions appeared at 4 years of age on the medial aspect of her left calf as small, hyperpigmented papules. Individual lesions enlarged and there was linear extension proximally. They were asymptomatic and there was no dissemination to other regions. No other family member had similar skin lesions.On examination, hyperkeratotic papules and plaques were distributed on her left lower limb along a line extending from the medial aspect of her calf to the midthigh. Individual lesions ranged in size from 0.5 cm to 2 cm. Smaller lesions were hyperpigmented, hyperkeratotic papules. Larger ones showed an annular configuration with atrophic centers surrounded by a fine raised border (Fig. 1).A skin biopsy specimen was obtained from the raised border of an annular lesion. A photomicrograph of the histopathology stained with hematoxylin-eosin is shown in Figure 2.

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Linear Warty Lesions in a Child

Cited by 8 publications

References 0 publications

Dermoscopy for the diagnosis of porokeratosis

Dermoscopy for the diagnosis of porokeratosis

Generalized linear porokeratosis

Unilateral Linear Annular Lesions in a Child

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