Linear focal elastosis

Linear focal elastosis: what's new?

“…The immature fibres are composed mainly of microfibrils that are contiguous to intracellular filaments of fibroblasts, their content of elastin is initially low but increases proportionally to their progressing sequential maturation. These findings support the conclusion that active elastogenesis is ongoing in the lesions 13,14 …”

Linear Focal Elastosis in a Family

“…6,7 In early stages it manifests as red atrophic band due to a continuum of elastolysis and elastosis differing only in stage of elastogenesis. 8,9 In later stages it manifests as yellow hypertrophic plaque due to focal increase in elastic fibres separating the dermal collagen bundles.…”