Limb loss.

Coffey, Laura; Desmond, Deirdre; Lombard-Vance, Richard; Jefferies, Philip; Wegener, Stephen T.

doi:10.1037/0000129-017

Cited by 3 publications

(1 citation statement)

References 145 publications

(200 reference statements)

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“…However, to the best of our knowledge, no longitudinal study has focused on the role and influence of anxiety and depression symptoms, in predicting clinical outcomes after LEA. Understandably, emotional symptoms are common in patients with DM and, especially, after a LEA (Desmond & Gallagher, 2008;Gallagher et al, 2019), but it is unclear whether there is any impact on short (1-month) and longterm (1-year) clinical outcomes as well as what is the differential role of depression and anxiety symptoms.…”

Section: Introductionmentioning

confidence: 99%

Anxiety and/or depression: which symptoms contribute to adverse clinical outcomes after amputation?

Pedras

Meira‐Machado

Carvalho

et al. 2020

Journal of Mental Health

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Background: One of the most serious complications of diabetes mellitus (DM) is a diabetic foot ulcer (DFU), with lower extremity amputation (LEA). Aims: This study aims to explore the role of anxiety and depression on mortality, reamputation and healing, after a LEA due to DFU. Methods: A sample of 149 patients with DFU who underwent LEA answered the Hospital Anxiety and Depression Scale and a sociodemographic and clinical questionnaire. This is a longitudinal and multicenter study with four assessment moments that used Cox proportional hazards models adjusted for demographic and clinical variables. Results: Rate of mortality, reamputation and healing, 10 months after LEA were 9.4%, 27.5% and 61.7%, respectively. Anxiety, at baseline, was negatively associated with healing. However, depression was not an independent predictor of mortality. None of the psychological factors was associated with reamputation. Conclusion: Results highlight the significant contribution of anxiety symptoms at pre-surgery, to healing after a LEA. Suggestions for psychological interventions are made.

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Section: Introductionmentioning

confidence: 99%