A waveguide-based chip-to-chip optical interconnection network on printed circuit board (PCB) was designed and fabricated, and experiments confirmed that the data rate in each channel could reach above 3.125 Gbit/s and the bit error rate (BER) could be up to 1.27Â10 -18 , which would be a good solution to solve the communication bottlenecks between high-speed very large scale integration chips. Besides, the whole design and fabrication of optical interconnection network on printed circuit board has the advantages of high reliable, low cost and ease of manufacture.