“…As one of the most prevalent chronic complications of diabetes, diabetic wounds are gaining widespread attention due to their difficulty of healing, and the etiology of this condition frequently results from persistent inflammation and cell dysfunction. 1 Wound repair is a complicated multifactor and multistep process that comprises phases of hemostasis, inflammation, proliferation, and remodeling, 2 and conventional therapies, including debridement, dressing changes and glucose-lowering treatment, do not seem to be effective in the treatment of diabetic wounds. However, newly developed drugs, including basic fibroblast growth factor and vascular endothelial growth factor, only apply to a specific phase of the wound repair process, and their therapeutic effects and clinical applications are also limited.…”