LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

Levine, Nicole L.; Zhang, Yidan; Hoang, Bang H.; Yan, Mingyu; Jurkowski, Zachary; Roth, Michael E.; Gill, Jonathan; Lo, Yungtai; Eisenberg, Ruth; Bekarev, Mikhail; Görlick, Richard; Geller, David S.

doi:10.5435/jaaos-d-18-00144

Cited by 9 publications

(10 citation statements)

References 23 publications

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“…In this study, the use of LigaSure™ had a significant effect in controlling intraoperative blood loss (p=0.0269) and blood transfusion rates (p=0.020). This is in line with a study by Levine et al (22), wherein they reported the effectiveness of LigaSure™ as a hemostatic tool in sarcoma surgeries compared to conventional hemostatic techniques. The use of LigaSure™ resulted in a significant decrease in mean intraoperative blood loss (336.4±400.8 vs. 577.2±812.9 ml; p=0.02) and blood transfusion volume (196.3±382.8 vs. 445.0±1,028.9 ml; p=0.04).…”

Section: Discussionsupporting

confidence: 91%

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Clinical Benefits of LigaSure™ for Surgical Amputation Without Tourniquet Use in Patients With Musculoskeletal Tumor

et al. 2023

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Background/Aim: Amputation is still a viable option for musculoskeletal tumors that are multi-compartmental, adjacent to neurovascular structures, and involving pathological fractures. Complications such as poor surgical margins, local recurrence and infection after limb salvage surgery are also indications for secondary amputation. An effective hemostatic technique is vital for preventing complications of massive blood loss and prolonged operative time. The use of LigaSure™ in the field of musculoskeletal oncology has not been well documented. Patients and Methods: This retrospective study included 27 patients with musculoskeletal tumor who underwent amputation using either LigaSure™ system (n=12) or traditional hemostatic technique (n=15) from 1999 to 2020. The purpose of this study was to evaluate the effect of LigaSure™ in terms of intra-operative blood loss, blood transfusion rates, and duration of surgery. Results: The use of LigaSure™ resulted in a significant decrease in intraoperative blood loss (p=0.027) and blood transfusion rates (p=0.020). There was no significant difference for the duration of surgery between the two groups (p=0.634). Conclusion: The LigaSure™ system can potentially improve clinical outcomes in patients with musculoskeletal tumor undergoing amputation surgeries. The LigaSure™ system is a safe and effective hemostatic tool for musculoskeletal tumor amputation surgeries.

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Section: Discussionsupporting

confidence: 91%

“…cause physiological imbalance, inadequate end-organ perfusion and, in the worst cases, can result in mortality (22,23). In this study, the use of LigaSure™ had a significant effect in controlling intraoperative blood loss (p=0.0269) and blood transfusion rates (p=0.020).…”

Section: Discussionmentioning

confidence: 59%

Clinical Benefits of LigaSure™ for Surgical Amputation Without Tourniquet Use in Patients With Musculoskeletal Tumor

et al. 2023

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“…The LigaSure energy device has significantly contributed to laparoscopic surgery to improve convenience and provide accurate sealing (9,11,13,14). It is typically used as a device for liver parenchymal dissection during laparoscopic hepatectomy and tissue division to achieve liver mobilization.…”

Section: Discussionmentioning

confidence: 99%

“…Energy devices enable safe ligation of blood vessels and tissues with a sealing effect absent in the conventional monopolar cautery. A LigaSure vessel-sealing device (Medtronics, Minneapolis, MN, USA) reduces the risk of bleeding during the dissection of vessels (9,(11)(12)(13)(14). Thus, it can be beneficial for the ligation of small vessels or tissues.…”

Section: Introductionmentioning

confidence: 99%

LigaSure versus monopolar cautery for recipient hepatectomy in liver transplantation: a propensity score-matched analysis

Lee¹,

Hong²,

Han³

et al. 2021

Ann Transl Med

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Background: Recipient hepatectomy during liver transplantation (LT) is one of the most challenging aspects of surgery due to the possibility of massive bleeding. This study aimed to compare and analyze the effectiveness between LigaSure and monopolar cautery in recipients.Methods: We reviewed 187 recipients who underwent LT from March 2019 to June 2020. We compared the surgical outcomes of the 69 recipients who underwent recipient hepatectomy with LigaSure (LigaSure group) and 118 recipients who underwent with monopolar cautery. Propensity score matching (PSM) was performed using the nearest-neighbor method at a ratio of 1:1 based on 14 baseline characteristics and possible factors that influence postoperative bleeding.Results: A total of 187 adult recipients were reviewed retrospectively. In the propensity score-matched analysis, The rates of bleeding and infectious complication were significantly lower in the LigaSure group than in the monopolar cautery group (3/69, 4.35% versus 13/69, 18.8%; P=0.015 and 1/69, 1.45% versus 9/69, 13.0%; P=0.017). The length of postoperative hospital stay was shorter in the LigaSure group (mean: 23.1±16.1 versus 39.6±58.2 days; P=0.024).Conclusions: Recipient hepatectomy with LigaSure is associated with a short hospital stay due to low reoperation rates, postoperative bleeding, and secondary infection related to bleeding.

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“…[9] In another study, the LigaSure™ system reduced the volume of blood transfusions and intraoperative blood loss. [10] In CABG, blood flow through the internal thoracic artery was found to be sufficient in a study to be used as a conduit. [11] Harmonic scalpel is a device that dissects and cauterizes the tissue simultaneously.…”

Section: Discussionmentioning

confidence: 99%

Comparison of electrocautery and LigaSure™ vessel sealing system in radial artery harvesting as coronary artery bypass surgery conduit: A prospective, randomized study

Ökten¹

2021

Cardiovasc Surg Int

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In this study, we aimed to compare the efficiency of electrocautery with the LigaSure™ vessel sealing system. Patients and methods:This randomized study included a total of 53 patients (44 males, 9 females; mean age: 63.7±8.4 years; range, 39 to 83 years) who underwent coronary artery bypass grafting (CABG) for radial artery (RA) harvesting with electrocautery or LigaSure™ vessel sealing system between January 2019 and September 2019. The patients were randomly assigned into two groups. Group 1 consisted of 27 patients operated with the LigaSure™ small jaw sealer/divider and Group 2 consisted of 26 patients operated with electrocautery. The length of the conduit, the amount of intraoperative blood loss, the number of hemostatic clips before and after the anastomosis, the amount of postoperative blood loss, the number of ecchymoses, hematoma and infection are compared. Results:The amount of blood loss from the beginning of harvesting to the end of the closure of the skin of left arm was significantly lower in Group 1 (p=0.004). The difference in the number of hemostatic clips before and after the anastomosis of RA to coronary artery was statistically significantly lower in Group 1 (p<0.001 and p<0.001, respectively). There was no statistically significant difference in the amount of blood loss postoperatively (p>0.6), number of ecchymoses (p>0.1), and postoperative hematoma (p>0.1) and infection (p>0.03) between the groups. Conclusion:Our study results suggest that the LigaSure™ vessel sealing system is a better option of RA harvesting, particularly in patients who are prone to bleed.

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LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

Cited by 9 publications

References 23 publications

Clinical Benefits of LigaSure™ for Surgical Amputation Without Tourniquet Use in Patients With Musculoskeletal Tumor

Clinical Benefits of LigaSure™ for Surgical Amputation Without Tourniquet Use in Patients With Musculoskeletal Tumor

LigaSure versus monopolar cautery for recipient hepatectomy in liver transplantation: a propensity score-matched analysis

Comparison of electrocautery and LigaSure™ vessel sealing system in radial artery harvesting as coronary artery bypass surgery conduit: A prospective, randomized study

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