Lifetime Multiplexing with Lanthanide Complexes for Luminescence In Situ Hybridisation

Abstract

Invited for this month's cover is the group of Yiqing Lu at Macquarie University, Sydney and colleagues at Dalian University of Technology. The cover picture shows photoluminescent sensing based on europium complexes emitting the same (red) colour but distinguishable lifetime (afterglow), which is attributed to a different coordination environment around the europium(3+) ion. More information can be found in the Research Article at 10.1002/anse.202100057.

Photoluminescent Inorganic Nanoprobe‐based Pathogen Detection

“…[39] In addition, Jia et al prepared three types of Erdoped NPs with distinguishable lifetimes from 100 μs to 1 ms. The designed in situ hybridization nanoprobes could be used for highly sensitive detection of the target bacterial species based on lifetime imaging, [40] which are usually more sensitive and more selective than conventional fluorescence detection methods. In addition, the lanthanide-doped upconversion NPs (UCNPs) can emit higher energy visible photons after absorbing low-energy near-infrared (NIR) photons, resulting in a high signal-to-noise ratio and light-penetration depth.…”