2018
DOI: 10.3349/ymj.2018.59.1.158
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Life-Threatening Thrombocytopenia Following Intravenous Contrast Media Infusion

Abstract: Radiocontrast media-induced acute severe thrombocytopenia is a very rare complication and potentially life-threatening. Here, we report the case of a 63-year-old male patient with severe acute thrombocytopenia following first exposure to intravenous non-ionic contrast media without immediate allergic reactions. His platelet count dropped from 107000/µL to 2000/µL after six hours of radiocontrast infusion. After administration of corticosteroid and transfusion of platelet concentrates, the platelet count return… Show more

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Cited by 6 publications
(9 citation statements)
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References 16 publications
(17 reference statements)
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“…Although a few case reports [1][2][3] have documented corticosteroid administration in similar situations, there is insufficient literature to support this intervention. Hence, we decided not to use IV corticosteroids.…”
Section: Discussionmentioning
confidence: 99%
“…Although a few case reports [1][2][3] have documented corticosteroid administration in similar situations, there is insufficient literature to support this intervention. Hence, we decided not to use IV corticosteroids.…”
Section: Discussionmentioning
confidence: 99%
“…Acute severe thrombocytopenia is an extremely rare and severe adverse complication induced by contrast media. To the best of our knowledge, 16 cases of this serious adverse reaction have been reported with different types of contrast media since the early 1980s (Table 3) [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. In most patients, any symptoms, including bleeding, fever, chills, dyspnea, wheezing, abdominal pain, and blood pressure variability, were observed within 24 h after contrast administration and the platelet count was decreased to below 10,000/ μl.…”
Section: Discussionmentioning
confidence: 99%
“…The lowest reported value of the platelet count was 0/ μl [16]. With regard to treatment, high-dose intravenous corticosteroids, which are widely used in management of anaphylaxis, were used in nine patients [2,4,6,7,10,12,13,16,17]. Eight patients received platelet transfusions [3, 5-8, 10, 12, 17].…”
Section: Discussionmentioning
confidence: 99%
“…In the current digital media environment, many scholars have discussed them. Park et al [1] believed that digital media have changed the art itself and the teaching method of aesthetic education in colleges and universities, and it was an important means to expand art teaching resources [1]. Xu et al [2] applied the teaching model he invented to practical teaching cases and found that the new teaching model can improve students' achievement by 20%.…”
Section: Related Workmentioning
confidence: 99%
“…erefore, it is necessary to design digital media teaching practice under the situation of media convergence. erefore, the innovation points of this study are as follows: (1) for the media fusion theory, this study adopts the current signal transmission mode and convex optimization theory for communication upgrade, so as to achieve better transmission e ect and provide a guarantee for students' learning. (2) For the teaching design of digital media, this study focuses on the function of adding subtitles and dividing videos.…”
Section: Introductionmentioning
confidence: 99%