Life Cycle of the gingival Epithelium in the artifically induced chronic Gingivitis in Mice

Abstract

The effect of chronic inflammation on the turnover of the gingival epithelium of the mouse was autoradiographically studied, using the H3-thymidine. Inflammation was artifically induced by applying croton oil to the site.No differrnce was observed in the migration pattern of the gingival epithelial cell, the cell migration being passive and being almost identical to that in normal. In epithelial attachement, the cell migration was observed from the stratum germinativum toward enamel, margin and/or stratum corneum through the complicated horizontal, vertical and diagonal direction.