Lidocaine versus ropivacaine for topical anesthesia in cataract surgery

Martini, E.; Cavallini, Gian Maria; Campi, L.; Lugli, N.; Neri, Giovanni; Molinari, Paolo

doi:10.1016/s0886-3350(01)01225-1

Cited by 34 publications

(38 citation statements)

References 14 publications

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“…In contrast, Mota et al (2009) and Oliva et al (2010), who performed the peribulbar block with 0.5% and 0.75% ropivacaine in cats and dogs, respectively, did not observed this symptom. Because ropivacaine is considered to be devoid of toxicity (AKERMAN;HELLBERG;TROSSVIK, 1988;LEW;VLOKA;HADŽIC, 2001;TORRES, 2006) even when used for ocular topical anesthesia (MARTINI et al, 2002), we assume that the symptoms observed may be related to the use of drugs of the same origin that differ from those used by Mota et al (2009) and Oliva et al (2010).…”

Section: Discussionmentioning

confidence: 99%

Ocular effects of retrobulbar block with different local anesthetics in healthy dogs

et al. 2014

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The objective of this study was to evaluate the ocular effects, the feasibility and the quality of retrobulbar block using the inferior temporal technique with different local anesthetics applied with the Tuohy epidural needle in dogs. Eight dogs were included in the experiment and each one was studied four times, with interval of 15 days between the treatments: Lido -2% lidocaine, Ropi -0.75% ropivacaine, Bupi -0.5% racemic bupivacaine and Levo -0.75% levobupivacaine. Except for the ropivacaine, all of the local anesthetics contained epinephrine at 1:200.000. The blocks were performed in the right eyes immediately after anesthetic induction, and the left eyes were not blocked and were used as controls. The intraocular pressure, tear production and corneal sensitivity were evaluated before any procedure (T0), 30 min after premedication (TMPA), 30 min after anesthetic induction (T30), after recovery from anesthesia (TREC), every 60 min up to 360 min and 12 and 24 h after the block. The pupil diameter was evaluated at the same time points, excepted at T0. The maximum pupillary dilatation was observed in Lido group at T120 followed by Ropi at TREC, and Bupi and Levo at T30. All of the anesthetics maintained eye pressure within acceptable levels for normal dogs and significantly reduced tear production. Tear production returned earliest in group Lido, followed by Bupi, Ropi and Levo. The corneal sensitivity returned earliest in group Lido, followed by Ropi, Bupi and Levo. The retrobulbar block using the temporal inferior technique proved to be feasible and safe, although lubrication of the ocular surface is suggested. Key words: Bupivacaine, dogs, levobupivacaine, lidocaine, ropivacaine ResumoO objetivo deste estudo foi avaliar os efeitos oculares, a exequibilidade e qualidade do bloqueio retrobulbar pela técnica inferior temporal, em cães, com diferentes anestésicos locais empregando-se agulha epidural de Tuohy. Oito cães foram incluídos no experimento e cada um foi estudado quatro vezes, com intervalo de 15 dias entre os tratamentos: Lido -lidocaína a 2%; Ropi -ropivacaína a 0,5%, Bupi -bupivacaína racêmica a 0,5% e Levo -levobupivacaína a 0,75%. Com exceção da ropivacaína, todos os anestésicos continham epinefrina 1:200.000. Os bloqueios foram realizados nos olhos direitos dos animais imediatamente após a indução anestésica, e os olhos esquerdos, não bloqueados, foram utilizados como controle. Avaliou-se a pressão intraocular, a produção lacrimal e a sensibilidade corneal antes de qualquer procedimento (T0), 30 min após a medicação pré-anestésica (TMPA), 30 min após a indução anestésica (T30), após a recuperação da anestesia (TREC), a cada 60 min até 360 min e 12 e 24 h após o bloqueio. O diâmetro pupilar foi avaliado nos mesmos momentos, exceto no T0. A máxima dilatação pupilar foi observada no grupo Lido seguida pelos grupos Ropi, Bupi e Levo. Todos os anestésicos mantiveram a pressão ocular dentro dos níveis normais para cães e reduziram significativamente a produção lacrimal. A produção lacrimal reto...

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Section: Discussionmentioning

confidence: 99%

Ocular effects of retrobulbar block with different local anesthetics in healthy dogs

et al. 2014

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“…29,30 Martini et al 12 showed that topical ropivacaine is safe in endothelial toxicity and seemed to be a good alternative to lidocaine, but could cause transient corneal oedema. None of our patients in the ropivacaine group displayed any kind of corneal oedema.…”

Section: Discussionmentioning

confidence: 99%

“…[8][9][10] Topical anaesthesia confers the advantages of relatively faster visual recovery and higher patient satisfaction, easy application, minimal discomfort on administration, rapid onset of anaesthesia, and lower cost. 5,[11][12][13] However, the use of a topical anaesthetic permits the patient's full ocular movement during surgery, requires patient compliance, and may involve the administration of supplemental anaesthesia. 5,12 Unpreserved lidocaine is the most frequently used and safest agent in topical anaesthesia.…”

Section: Introductionmentioning

confidence: 99%

“…5,[11][12][13] However, the use of a topical anaesthetic permits the patient's full ocular movement during surgery, requires patient compliance, and may involve the administration of supplemental anaesthesia. 5,12 Unpreserved lidocaine is the most frequently used and safest agent in topical anaesthesia. Because of the shortacting effect, intraoperative and/or postoperative pain, and dissatisfaction may be associated with the use of topical lidocaine.…”

Section: Introductionmentioning

confidence: 99%

“…Studies have shown that topical ropivacaine is at least as effective as lidocaine and is safe for use as a topical anaesthetic, although its onset of action is slower than that of lidocaine. 12,16,17 Levobupivacaine, the S (À) isomer of bupivacaine, is less cardiotoxic than racemic bupivacaine. Ropivacaine is the first single isomer found, while levobupivacaine is the second to be studied clinically as a pure single isomer.…”

Section: Introductionmentioning

confidence: 99%

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Comparative clinical trial of topical anaesthetic agents for cataract surgery with phacoemulsification: lidocaine 2% drops, levobupivacaine 0.75% drops, and ropivacaine 1% drops

Borazan

Karalezlı

Akova

et al. 2007

Eye

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Purpose To assess the safety and efficacy of topical lidocaine, levobupivacaine, and ropivacaine in cataract surgery with phacoemulsification. Methods One hundred and five patients scheduled for cataract surgery with topical anaesthesia were randomly allocated into 3 groups of 35 patients each to receive eye drops of lidocaine 2%, levobupivacaine 0.75%, or ropivacaine 1% every 5 min starting 30 min before surgery. Patients graded their pain using a 0-10-point verbal pain score (VPS) at different stages of the procedure. The levels of patient and surgeon satisfaction, the duration of surgery, complications, and the need for supplemental anaesthesia were recorded. Results There was no significant difference in duration of surgery and demographic variables among the groups. At the intraoperative period, end of surgery, and postoperative first hour the mean VPS in the lidocaine group was significantly higher than the others (Po0.01), but no significant difference was found between the levobupivacaine and ropivacaine groups. At incision and 24 h after surgery, it was not significantly different among the groups. Surgeon and patient satisfaction scores were significantly better in the levobupivacaine and ropivacaine groups than in the lidocaine group (Po0.01).Conclusions Topical anaesthesia with levobupivacaine and ropivacaine were safe, feasible and more effective than lidocaine in cataract surgery. Levobupivacaine and ropivacaine provided sufficient and long-lasting analgesia without the need of supplemental anaesthesia for each patient.

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Topical and Intracameral Anaesthesia for Cataract Surgery

Bellucci

Morselli

2005

Cataract and Refractive Surgery

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Lidocaine versus ropivacaine for topical anesthesia in cataract surgery

Abstract: Topical ropivacaine performed at least as well as topical lidocaine in efficacy and safety in cataract surgery. It provided sufficient and long-lasting analgesia without the need for supplemental intracameral anesthesia in most cases.

Cited by 34 publications

References 14 publications

Ocular effects of retrobulbar block with different local anesthetics in healthy dogs

Ocular effects of retrobulbar block with different local anesthetics in healthy dogs

Comparative clinical trial of topical anaesthetic agents for cataract surgery with phacoemulsification: lidocaine 2% drops, levobupivacaine 0.75% drops, and ropivacaine 1% drops

Topical and Intracameral Anaesthesia for Cataract Surgery

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