Lichenoid folliculitis: A unifying concept

Turegano, Mamina M.; Sperling, Leonard C.

doi:10.1111/cup.12938

Cited by 21 publications

(23 citation statements)

References 85 publications

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“…Recently, a unifying concept of “LF” has been proposed by Turegano et al ., to describe all entities presenting with follicular papules and scarring alopecia, scalp or nonscalp, with lichenoid histology. This potentially could throw more light on shared pathogenesis and treatment options.…”

Section: Demographic Details and Clinical Presentation Of Four Patientsmentioning

confidence: 99%

Lichen planopilaris beyond scalp: a case series with dermoscopy‐histopathology correlation

Arshdeep¹,

Batrani²,

Kubba³

et al. 2018

Int J Dermatology

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Section: Demographic Details and Clinical Presentation Of Four Patientsmentioning

confidence: 99%

Lichen planopilaris beyond scalp: a case series with dermoscopy‐histopathology correlation

Arshdeep¹,

Batrani²,

Kubba³

et al. 2018

Int J Dermatology

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“…Lichenoid folliculitis with lichenoid interface dermatitis is characteristic of the LPP group of disorders, subclassified into two subgroups: keratosis pilaris atrophicans (KPA; including keratosis pilaris atrophicans faciei/ulerythema ophryogenes, atrophoderma vermiculatum and keratosis follicularis spinulosa decalvans [KFSD]); and the lichen planopilaris (LPP) subgroup (including LPP, frontal fibrosing alopecia [FFA], Graham‐Little‐Piccardi‐Lassueur syndrome and fibrosing alopecia in a pattern distribution [FAPD]) . According to Turegano and Sperling, both subgroups show unifying histological and clinical similarities, suggesting that most of these conditions have overlapping features with those seen in other members of the lichenoid inflammation family.…”

Section: Discussionmentioning

confidence: 99%

“…Turegano and Sperling also proposed the term LF as a simpler paradigm to be used for this group of diseases, instead of dividing them into two distinct subgroups. As of yet, LI and other ichthyosiform syndromes, such as CHHS, are not included in the group of primary lymphocytic cicatricial alopecia.…”

Section: Discussionmentioning

confidence: 99%

Lichenoid folliculitis of the scalp in four patients with ichthyosiform skin disorders and cicatricial alopecia

et al. 2019

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Ichthyosis is a heterogeneous group of inherited skin disorders characterized by a defect of keratinization. Patients diagnosed with lamellar ichthyosis (LI) and some ichthyosiform syndromes, such as the Conradi-Hünermann-Happle syndrome (CHHS), usually present with hair loss. Even though only few dermatologic complaints carry as many emotional overtones as hair loss, there are very few data available in the literature regarding scalp histopathological features in ichthyosis. A better understanding of scalp changes in such context may result in new therapeutic strategies that in turn would enhance patients' self-esteem and quality of life. The aim of this paper is to describe the scalp histopathological findings of four young patients with cicatricial alopecia: three diagnosed as having LI and the fourth with CHHS. K E Y W O R D S alopecia, dermatopathology, hair follicle 1 | INTRODUCTION Ichthyosis is a heterogeneous group of inherited skin disorders characterized by a defect of keratinization 1-4 with an estimated incidence of 1:200000 ± 300 000. 3 Patients bearing lamellar ichthyosis (LI) and some ichthyosiform syndromes, such as the Conradi-Hünermann-Happle syndrome (CHHS), present with ichthyosiform skin lesions and also scalp involvement, sometimes manifested as unambiguous cicatricial alopecia. In fact, few dermatological complaints carry as many emotional overtones as hair loss. 5 Yet, despite the considerable psychological impairment recognized in patients suffering from ichthyosis, there are very few data available in the literature regarding scalp histopathological features. Hence, a better understanding of scalp changes may result in new therapeutic strategies that in turn would enhance patients' self-esteem and quality of life. In order to highlight histopathological findings, the authors present four cases of overt cicatricial alopecia in young females who have been followed since childhood for ichthyosiform skin changes. Three out of the four patients were diagnosed as having LI and the fourth with CHHS. 2 | CASE REPORTS 2.1 | Cases 1 and 2 Two sisters with LI complained of long-term duration of hair loss and scalp scaling. Both had been followed by a pediatric dermatologist since their childhood. On physical examination, the 15-year-old sister showed frontotemporal hair loss, a central area of patchy cicatricial alopecia and dry, brittle hair (Figure 1). The 24-year-old sister exhibited frontotemporal hairline recession and dry, brittle hair (Figure 2). Dermoscopic and histopathological features are shown in Figures 3-6 and 7.2.2 | Case 3 A 22-year-old female patient with LI complained of hair loss since her early adolescence. On physical examination, there were frontotemporal hairline recession, occipital patchy cicatricial alopecia, sparse pustules and dry, brittle hair (Figure 8). Dermoscopic and histopathological features are shown in Figures 9-10 and 11.

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“…Histologically, significant overlap exists among keratosis pilaris variants and other follicular inflammatory disorders. Turegano et al proposed the term “lichenoid folliculitis” as a unifying terminology for KPA and lichen planopilaris given histologic similarity and presence of lichenoid infiltration seen in both spectra of disease. To our knowledge, mucin deposition has not been reported as a histological finding of KP.…”

Section: Introductionmentioning

confidence: 99%

Keratosis pilaris rubra with mucin deposition

et al. 2018

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Keratosis pilaris (KP) is a benign cutaneous disorder characterized by folliculocentric hyperkeratotic papules most often occurring on the proximal extremities. Erythema is usually limited to perifollicular skin, but when keratosis pilaris presents on a background of confluent erythema, the term keratosis pilaris rubra (KPR) is used. The histological findings associated with KP have not been well described in the literature. Herein, we present a case of a 14-year-old male with a 7-year history of erythema and follicular-based papules over his bilateral cheeks, consistent with KPR. Histological examination revealed abundant mucin, keratotic follicular plugging, and periadnexal lymphocytosis. Our novel finding of abundant dermal mucin expands the histopathologic description of KPR. K E Y W O R D S keratosis pilaris, keratosis pilaris rubra, mucin /journal/cup J Cutan Pathol. 2018;45:958-961.

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Lichenoid folliculitis: A unifying concept

Cited by 21 publications

References 85 publications

Lichen planopilaris beyond scalp: a case series with dermoscopy‐histopathology correlation

Lichen planopilaris beyond scalp: a case series with dermoscopy‐histopathology correlation

Lichenoid folliculitis of the scalp in four patients with ichthyosiform skin disorders and cicatricial alopecia

Keratosis pilaris rubra with mucin deposition

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