Lichen spinulosus after the ingestion of omeprazole

Severe erythrodermic reactions to the proton pump inhibitors omeprazole and lansoprazole

“…There have been occasional case reports of other types of reactions to PPIs and these include acute generalized exanthematous pustulosis (to lansoprazole), and pityriasis rosea, erythema nodosum and acute disseminated epidermal necrosis (with omeprazole) 7 –12 . PPIs may cause potentially severe drug eruptions.…”