Levonorgestrel-Releasing Intrauterine Device

Luukkainen, Tapani; Lähteenmäki, Pekka; Toivonen, Juhani

doi:10.3109/07853899009147248

Cited by 185 publications

(121 citation statements)

References 18 publications

(1 reference statement)

Supporting

Mentioning

102

Contrasting

Unclassified

Order By: Relevance

“…The response of ovaries to an LNG-IUS is directly linked to serum levels of levonogestrel. More than 50 µg of levonorgestrel is required on a daily basis to suppress ovulation, but an LNG-IUS releases only 20 µg of levonorgestrel a day [5]. As the serum level of levonorgestrel varies largely among women; the inhibition of ovulation with an LNG-IUS occurs in very few women.…”

Section: Introductionmentioning

confidence: 99%

Menstrual Bleeding Patterns and Development of Ovarian Cysts in Turkish Levonorgestrel- Releasing Intrauterine System Users

Naykı¹,

Naykı²,

Ulug³

et al. 2015

J Health Med Informat

View full text Add to dashboard Cite

Objective: The levonorgestrel-releasing intrauterine system (LNG-IUS) is a long acting, safe, and reversible method that has a strong contraceptive effect. When using this method, menstrual bleeding disturbance and functional ovarian cysts are common. The objective of this study is to evaluate the relationship between using LNG-IUSs with the development of a functional ovarian cyst and bleeding disturbance in Turkish women Material and methods: This is a prospective study including 273 Turkish women with regular menstrual cycles who had been administered LNG-IUS for contraception. We assessed their one-year follow-up results regarding bleeding patterns and functional ovarian cysts. Results:Oligomenorrhea was the most commonly seen menstrual bleeding disorder, seen in 13.5% of all subjects. Oligomenorrhea occurred in the 4-6th months of using a LNG-IUS in 70.27% of the subjects. During the one-year follow-up, 28% of the subjects who were administered LNG-IUSs had ovarian cysts. While 36.36% of the ovarian cysts occurred within 4-6 months, 57.14% of them appeared between 7-12 months. Conclusion:During 1-year short-term follow-up of those using LNG-IUSs, approximately one thirds of the subjects developed functional ovarian cysts and 13.5% of all complained of oligomenorrhea.

show abstract

Section: Introductionmentioning

confidence: 99%

Menstrual Bleeding Patterns and Development of Ovarian Cysts in Turkish Levonorgestrel- Releasing Intrauterine System Users

Naykı¹,

Naykı²,

Ulug³

et al. 2015

J Health Med Informat

View full text Add to dashboard Cite

show abstract

“…Up to 50% of women stop using IUDs within 5 years, most often because of unacceptable vaginal bleeding or pain [8]. The frequency of removals for bleeding problems (including amenorrhea) is similar in copper IUD users and the levonorgestrel intrauterine system (LNG-IUS) users: 14% in copper T users and 11% in LNG-IUS users after 36 months of use [9]. The aim of this study was to detect the relationship between IUD failures and some factors such as length of tail, IUD experience, education level, utilization period, gravidy, parity, age and length of uterine cavity.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of risk factors for intrauterine device failure

Açmaz¹

2012

CMJ

View full text Add to dashboard Cite

Aim. The aim of this study was to detect the relationship between IUD failure and some factors such as length of tail, IUD experience, education level, utilization period, gravidy, parity, age and length of uterine cavity. Methods. Our study groups included 48 patients who were randomly admitted to our clinic for problematic IUD and 30 normal patients without any complaints who were admitted to our clinic with out of date IUD who wanted new IUD insertion or desired to become pregnant as control group. Both groups were evaluated for the demographic characteristics such as education level, history of abortion, menstrual regulation, and type of delivery, IUD experience and blood count, duration of IUD use, length of tail, type of IUD, and length of uterine cavity. Results. We detected statistically significant results for length of cavity, length of tail, education level and IUD experience. Conclusion. We are in the opinion that length of uterine cavity, length of IUD tail, educational level and IUD experience are associated with IUD failure. Keywords: Contraception, intrauterine devices, copper ÖzetAmaç. Bu çalışmanın amacı RİA kullanımında başarısızlık ile rahim kavite uzunluğu, eğitim seviyesi, RİA ipinin uzunluğu, kullanım süresi, RİA tecrübesi, gravida, parite ve yaş gibi bazı faktörlerin ilişkisinin incelenmesidir. Yöntemler. Kliniğimize rastgele başvuran problemli spirali olan 48 hasta bizim çalışma gurubumuzu oluşturmuştur ve hiçbir yakınması olmayan spiralinin günü geçtiği için yeni spiral isteyen veya bebek yapmayı planlayan 30 hasta kontrol gurubumuzu oluşturmuştur. Her iki gurup demografik özellikler, eğitim seviyesi, düşük öyküsü, adet düzeni, doğum şekli, RİA tecrübesi ve kan sayımı, spiralin kullanım süresi, tipi, kuyruk uzunluğu ve rahim kavitesinin uzunluğu açısından karşılaştırılmıştır. Bulgular. RİA ipinin uzunluğu, kavite uzunluğu, eğitim seviyeleri ve RİA tecrübesi açısından istatistiksel olarak anlamlı sonuçlar saptadık. Sonuç. Biz RİA ipinin uzunluğu, kavite uzunluğu, eğitim seviyeleri ve RİA tecrübesinin spiral kullanımındaki başarısızlıkla ilişkili olduğu düşüncesindeyiz. Anahtar sözcükler: Kontrasepsiyon, rahim içi araç, bakırGeliş tarihi

show abstract

“…It is effective for 5 years, and during this period, the cylinder releases, via a drug-contolling membrane, 20 µg of LNG per 24 hours. 11 LNG, delivered to the uterine cavity, is absorbed systemically, and maximum serum levels are reached within a few hours; systemic serum levels are maintained at around 150-200 pg/ml. 12 LNG-IUS insertion results in immediate and profound effects upon endometrial morphology and function, with extensive decidualization of the endometrial stromal cells, atrophy of the glandular and surface epithelium and changes in vascular morphology.…”

mentioning

confidence: 99%