Levels of Serum Immunoglobulins and Complements in Patients With Visceral Leishmaniasis

Shani, Wafaa Sadoon

doi:10.33762/bvetr.2006.58652

Cited by 1 publication

(1 citation statement)

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“…However the present study in consistent with [12,13] who mentioned that the highest level of C4 in women with positive anti Toxoplasma IgM while the lowest level of C4 was in women with negative anti Toxoplasma IgM, and [14] reported that, significant differences were reported in the levels of C4 between the serum of infected women in comparison with no infected one.…”

Section: Discussionsupporting

confidence: 92%

Assessment of C3 and C4 component of complement system in aborted women infected with Toxoplasma gondii

Fadhil al kalaby,

A. Sultan,

N. AL-Fatlawi

2017

Qad Med J

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Background: The complement system consists of more than 30 proteins that are either present as soluble proteins in the blood or present as membrane-associated proteins. Inappropriate complement activation and complement deficiencies are the underlying cause of the pathophysiology of many diseases.Methods: A case-control study was conducted to asses role of complement system during toxoplasmosis in Najaf province. Thirty five sera of infected women with toxoplasmosis by investigation antibody against toxoplasmosis for IgG and IgM by ELISA technique were tested to determine the levels of C3 and C4 by using single radial immunodiffusion technique and compared with the ten of control sera of non infected subjects and non-aborted.Results: The high C3 in significant differences(P<0.05) and C4 with no significant differences(P>0.05) levels were found in aborted toxo-positive women in compared with control. Likewise, it was found that association between concentration of C3,C4 and number of abortion.Conclusion: complement were play role in immune response of pregnant women especially against toxoplasmosis that cause abortion to these women.

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Section: Discussionsupporting

confidence: 92%