“…The recent literature on Alternaria toxins has shown that the most suitable technique to analyze Alternaria toxins in food is liquid chromatography–tandem mass spectrometry (LC-MS/MS) [ 6 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. The research articles and inhouse validation of the candidate standard method focused on the significant matrix effect (ME) [ 13 , 14 ], which greatly influences the LC-MS/MS analysis of Alternaria toxins in food matrices [ 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Consequently, isotope dilution mass spectrometry (...…”